CAS 660868-91-7 GW843682X - Analytical Products / Alfa Chemistry

CAT	AP660868917-A
CAS	660868-91-7
Structure
MDL Number	MFCD09971143
Molecular Weight	477.46
InChI Key	JSKUWFIZUALZLX-UHFFFAOYSA-N

Description	≥98% (HPLC), solid
Solubility	DMSO: >10 mg/mL
Assay	≥98% (HPLC)
Color	off-white
Form	solid
Size	1MG, 5MG
Storage Conditions	2-8°C

1

An In-Vitro Evaluation of the Polo-Like Kinase Inhibitor GW843682X Against Paediatric Malignancies

Kristina Spaniol, Joachim Boos, Claudia Lanvers-Kaminsky

Anticancer Drugs. 2011 Jul;22(6):531-42.

PMID: 21637161

1

Polo-like Kinase 1 (PLK1) Is Involved in Toll-Like Receptor (TLR)-mediated TNF-α Production in Monocytic THP-1 Cells

Jinyue Hu, Guihua Wang, Xueting Liu, Lina Zhou, Manli Jiang, Li Yang

PLoS One. 2013 Oct 18;8(10):e78832.

PMID: 24205328

1

Polo-like Kinase 1 Inhibition Causes Decreased Proliferation by Cell Cycle Arrest, Leading to Cell Death in Glioblastoma

J A Pezuk, M S Brassesco, A G Morales, J C de Oliveira, R G de Paula Queiroz, H R Machado, C G Carlotti Jr, L Neder, C A Scrideli, L G Tone

Cancer Gene Ther. 2013 Sep;20(9):499-506.

PMID: 23887645

1

Polo-Like Kinase 1 Pharmacological Inhibition as Monotherapy or in Combination: Comparative Effects of Polo-Like Kinase 1 Inhibition in Medulloblastoma Cells

Julia Alejandra Pezuk, Maria Sol Brassesco, Priscila Maria Manzini Ramos, Carlos Alberto Scrideli, Luiz Gonzaga Tone

Anticancer Agents Med Chem. 2017;17(9):1278-1291.

PMID: 28270075

1

The Cytotoxic Effect of GW843682X on Nasopharyngeal Carcinoma

Qinyong Hu, Yuxin Chu, Weiguo Hu, Min Peng, Qibin Song

Anticancer Agents Med Chem. 2016;16(12):1640-1645.

PMID: 27198987

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