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GW9662

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For Research Use Only | Not For Clinical Use
CATAP22978252
CAS22978-25-2
Structure
MDL NumberMFCD01215270
Molecular Weight276.68
InChI KeyDNTSIBUQMRRYIU-UHFFFAOYSA-N
Description>98% (HPLC)
SolubilityDMSO: 26 mg/mL; H2O: insoluble
Assay>98% (HPLC)
Colorwhite
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Structural Mechanism for Directing Corepressor-Selective Inverse Agonism of PPARγ

Richard Brust, Jinsai Shang, Jakob Fuhrmann, Sarah A Mosure, Jared Bass, Andrew Cano, Zahra Heidari, Ian M Chrisman, Michelle D Nemetchek, Anne-Laure Blayo, Patrick R Griffin, Theodore M Kamenecka, Travis S Hughes, etc.

Nat Commun. 2018 Nov 8;9(1):4687.

PMID: 30409975

1

Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells

Anke Jaudszus, Stefan Lorkowski, Michael Gruen, Alexander Roth, Gerhard Jahreis

Int J Inflam. 2014;2014:149628.

PMID: 25054074

1

Myeloid Peroxisome Proliferator-Activated Receptor Gamma Deficiency Aggravates Myocardial Infarction in Mice

Zhu-Xia Shen, Qing-Zhen Yang, Chao Li, Lin-Juan Du, Xue-Nan Sun, Yan Liu, Jian-Yong Sun, Hui-Hui Gu, Yu-Min Sun, Jun Wang, Sheng-Zhong Duan

Atherosclerosis. 2018 Jul;274:199-205.

PMID: 29800789

1

Scutellarin Ameliorates Nonalcoholic Fatty Liver Disease Through the PPARγ/PGC-1α-Nrf2 Pathway

Xiaoxue Zhang, Renpeng Ji, Huijun Sun, Jinyong Peng, Xiaodong Ma, ChangYuan Wang, Yufeng Fu, Liuchi Bao, Yue Jin

Free Radic Res. 2018 Feb;52(2):198-211.

PMID: 29400110

1

The PPAR-γ Antagonist GW9662 Elicits Differentiation of M2c-like Cells and Upregulation of the MerTK/Gas6 Axis: A Key Role for PPAR-γ in Human Macrophage Polarization

Gaetano Zizzo, Philip L Cohen

J Inflamm (Lond). 2015 May 3;12:36.

PMID: 25972766

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