CAS 192065-56-8 GYKI 52466 hydrochloride - Analytical Products / Alfa Chemistry

CAT	AP192065568
CAS	192065-56-8
Structure
MDL Number	MFCD00153803
Molecular Weight	329.78
InChI Key	RUBSCPARMVJNKX-UHFFFAOYSA-N

Description	solid
Solubility	DMSO: 0.39 mg/mL; ethanol: 0.4 mg/mL; 0.1 M HCl: 0.68 mg/mL; methanol: 1 mg/mL; H2O: >10 mg/mL
Assay	≥98% (HPLC)
Color	yellow
Form	solid
Size	10MG, 25MG, 100MG

1

Cerebroprotective Effect of a non-N-methyl-D-aspartate Antagonist, GYKI 52466, After Focal Ischemia in the Rat

S E Smith, B S Meldrum

Stroke. 1992 Jun;23(6):861-4.

PMID: 1595106

1

Effect of the non-NMDA Receptor Antagonist GYKI 52466 on the Microdialysate and Tissue Concentrations of Amino Acids Following Transient Forebrain Ischaemia

B Arvin, D Lekieffre, J L Graham, C Moncada, A G Chapman, B S Meldrum

J Neurochem. 1994 Apr;62(4):1458-67.

PMID: 7907651

1

GYKI 52466 [1-(4-aminophenyl)-4-methoxy-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride] and the Anticonvulsive Activity of Conventional Antiepileptics Against Pentetrazol in Mice

S J Czuczwar, M Gasior, R Kamiński, Z Kleinrok, M Kozicka, G Ossowska, T Pietrasiewicz

Mol Chem Neuropathol. 1998 Apr;33(3):149-62.

PMID: 9642669

1

GYKI 52466 and Related 2,3-benzodiazepines as Anticonvulsant Agents in DBA/2 Mice

G de Sarro, A Chimirri, A De Sarro, R Gitto, S Grasso, P Giusti, A G Chapman

Eur J Pharmacol. 1995 Dec 29;294(2-3):411-22.

PMID: 8750701

1

GYKI 52466 Blocks the Increase in Extracellular Glutamate Induced by Ischaemia

B Arvin, C Moncada, E Le Peillet, A Chapman, B S Meldrum

Neuroreport. 1992 Mar;3(3):235-8.

PMID: 1355369

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