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HC-030031

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For Research Use Only | Not For Clinical Use
CATAP349085387-A
CAS349085-38-7
MDL NumberMFCD02007349
Molecular Weight355.39
InChI KeyHEQDZPHDVAOBLN-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size10MG, 50MG
Storage Conditionsroom temp
1

Blockade of TRPA1 With HC-030031 Attenuates Visceral Nociception by a Mechanism Independent of Inflammatory Resident Cells, Nitric Oxide and the Opioid System

L M S Pereira, R C P Lima-Júnior, A X C Bem, C G Teixeira, L S Grassi, R P Medeiros, R D Marques-Neto, R B Callado, K S Aragão, D V T Wong, M L Vale, G A C Brito, R A Ribeiro

Eur J Pain. 2013 Feb;17(2):223-33.

PMID: 22689151

1

Effect of TRPA1 Activator Allyl Isothiocyanate (AITC) on Rat Dural and Pial Arteries

Anna Koldbro Hansted, Deepak Kumar Bhatt, Jes Olesen, Lars Jørn Jensen, Inger Jansen-Olesen

Pharmacol Rep. 2019 Aug;71(4):565-572.

PMID: 31132686

1

HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- And Neuropathy-Induced Mechanical Hypersensitivity

Samer R Eid, Eric D Crown, Eric L Moore, Hongyu A Liang, Kar-Chan Choong, Shelley Dima, Darrell A Henze, Stefanie A Kane, Mark O Urban

Mol Pain. 2008 Oct 27;4:48.

PMID: 18954467

1

Inhibition of TRPA1 Attenuates Doxorubicin-Induced Acute Cardiotoxicity by Suppressing Oxidative Stress, the Inflammatory Response, and Endoplasmic Reticulum Stress

Zhen Wang, Menglong Wang, Jianfang Liu, Jing Ye, Huimin Jiang, Yao Xu, Di Ye, Jun Wan

Oxid Med Cell Longev. 2018 Feb 28;2018:5179468.

PMID: 29682158

1

Structural Basis of TRPA1 Inhibition by HC-030031 Utilizing Species-Specific Differences

Rupali Gupta, Shigeru Saito, Yoshiharu Mori, Satoru G Itoh, Hisashi Okumura, Makoto Tominaga

Sci Rep. 2016 Nov 22;6:37460.

PMID: 27874100

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