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Heparin Sodium with Oversulfated Chondroitin Sulfate

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For Research Use Only | Not For Clinical Use
CATCS31041821
DescriptionUnited States Pharmacopeia (USP) Reference Standard
Size8.8MG
1

Case Study: Contamination of Heparin With Oversulfated Chondroitin Sulfate

Edward K Chess, Shawn Bairstow, Shane Donovan, Karalyn Havel, Peifeng Hu, Richard J Johnson, Sarah Lee, Jeff McKee, Reagan Miller, Edwin Moore, Mark Nordhaus, Joseph Ray, Christina Szabo, Todd Wielgos

Handb Exp Pharmacol. 2012;(207):99-125.

PMID: 22566223

1

Highly Sensitive Ratiometric Detection of Heparin and Its Oversulfated Chondroitin Sulfate Contaminant by Fluorescent Peptidyl Probe

Pramod Kumar Mehta, Hyeri Lee, Keun-Hyeung Lee

Biosens Bioelectron. 2017 May 15;91:545-552.

PMID: 28086125

1

Oversulfated Chondroitin Sulfate and OSCS-contaminated Heparin Cause Dose- And Route-Dependent Hemodynamic Effects in the Rat

Alain Corbier, Nathalie Le Berre, David Rampe, Harry Meng, Martin Lorenz, Pascale Vicat, Sophie Potdevin, Michel Doubovetzky

Toxicol Sci. 2011 Jun;121(2):417-27.

PMID: 21436127

1

Oversulfated Chondroitin Sulfate Interaction With Heparin-Binding Proteins: New Insights Into Adverse Reactions From Contaminated Heparins

Boyangzi Li, Jiraporn Suwan, Jeffrey G Martin, Fuming Zhang, Zhenqing Zhang, Debra Hoppensteadt, Melanie Clark, Jawed Fareed, Robert J Linhardt

Biochem Pharmacol. 2009 Aug 1;78(3):292-300.

PMID: 19389385

1

Sensitive Detection of Oversulfated Chondroitin Sulfate in Heparin Sodium or Crude Heparin With a Colorimetric Microplate Based Assay

Cynthia D Sommers, Daniel J Mans, Laura C Mecker, David A Keire

Anal Chem. 2011 May 1;83(9):3422-30.

PMID: 21449571

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