0

HLM006474

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP353519638
CAS353519-63-8
MDL NumberMFCD02168344
Molecular Weight399.48
InChI KeyCYNZBLNMIJNBSF-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Small-Molecule E2F Inhibitor Blocks Growth in a Melanoma Culture Model

Yihong Ma, Courtney A Kurtyka, Sandhya Boyapalle, Shen-Shu Sung, Harshani Lawrence, Wayne Guida, W Douglas Cress

Cancer Res. 2008 Aug 1;68(15):6292-9.

PMID: 18676853

1

E2F Inhibition Synergizes With Paclitaxel in Lung Cancer Cell Lines

Courtney A Kurtyka, Lu Chen, W Douglas Cress

PLoS One. 2014 May 15;9(5):e96357.

PMID: 24831239

1

HO-1 Promotes Resistance to an EZH2 Inhibitor Through the pRB-E2F Pathway: Correlation With the Progression of Myelodysplastic Syndrome Into Acute Myeloid Leukemia

Zhengchang He, Siyu Zhang, Dan Ma, Qin Fang, Liping Yang, Shaoxian Shen, Ying Chen, Lingli Ren, Jishi Wang

J Transl Med. 2019 Nov 11;17(1):366.

PMID: 31711520

1

Improved Synthesis, Resolution, Absolute Configuration Determination and Biological Evaluation of HLM006474 Enantiomers

Miyanou Rosales-Hurtado, Alexandre Lebeau, Cyril Bourouh, Gerardo Cebrian-Torrejon, Muriel Albalat, Marion Jean, Jean-Valère Naubron, Jean-Sébastien Annicotte, Zohra Benfodda, Patrick Meffre

Bioorg Med Chem Lett. 2019 Feb 1;29(3):380-382.

PMID: 30578036

1

Inhibition of Skp2 Sensitizes Lung Cancer Cells to Paclitaxel

Tonghai Huang, Lin Yang, Guangsuo Wang, Guanggui Ding, Bin Peng, Yuxin Wen, Zheng Wang

Onco Targets Ther. 2017 Jan 18;10:439-446.

PMID: 28176922

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Online Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode