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HTH-01-015

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For Research Use Only | Not For Clinical Use
CATAP1613724427
CAS1613724-42-7
MDL NumberMFCD28167816
Molecular Weight468.55
InChI KeyCHSDJDLAKKAWCI-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Characterization of WZ4003 and HTH-01-015 as Selective Inhibitors of the LKB1-tumour-suppressor-activated NUAK Kinases

Sourav Banerjee, Sara J Buhrlage, Hai-Tsang Huang, Xianming Deng, Wenjun Zhou, Jinhua Wang, Ryan Traynor, Alan R Prescott, Dario R Alessi, Nathanael S Gray

Biochem J. 2014 Jan 1;457(1):215-25.

PMID: 24171924

1

Functional Genomics Identifies Specific Vulnerabilities in PTEN-deficient Breast Cancer

Yew Chung Tang, Szu-Chi Ho, Elisabeth Tan, Alvin Wei Tian Ng, John R McPherson, Germaine Yen Lin Goh, Bin Tean Teh, Frederic Bard, Steven G Rozen

Breast Cancer Res. 2018 Mar 22;20(1):22.

PMID: 29566768

1

Interplay Between Polo Kinase, LKB1-activated NUAK1 Kinase, PP1βMYPT1 Phosphatase Complex and the SCFβTrCP E3 Ubiquitin Ligase

Sourav Banerjee, Anna Zagórska, Maria Deak, David G Campbell, Alan R Prescott, Dario R Alessi

Biochem J. 2014 Jul 15;461(2):233-45.

PMID: 24785407

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