CAS 9004-64-2 Hydroxypropyl cellulose - Analytical Products / Alfa Chemistry

CAT	AP9004642
CAS	9004-64-2
Structure
MDL Number	MFCD00132688

Green Electrospining of Hydroxypropyl Cellulose Nanofibres for Drug Delivery Applications

Mohamed H El-Newehy, Mehrez E El-Naggar, Saleh Alotaiby, Hany El-Hamshary, Meera Moydeen, Salem Al-Deyab

J Nanosci Nanotechnol. 2018 Feb 1;18(2):805-814.

PMID: 29448497

Hydroxypropyl Cellulose as a Green Polymer for Thermo-Responsive Aqueous Foams

Eric Weißenborn, Björn Braunschweig

Soft Matter. 2019 Apr 7;15(13):2876-2883.

PMID: 30843017

Hydroxypropyl Cellulose Photonic Architectures by Soft Nanoimprinting Lithography

André Espinha, Camilla Dore, Cristiano Matricardi, Maria Isabel Alonso, Alejandro R Goñi, Agustín Mihi

Nat Photonics. 2018 Jun;12(6):343-348.

PMID: 29881447

Side Chain Effect of Hydroxypropyl Cellulose Derivatives on Reflection Properties

Kenichiro Hayata, Seiichi Furumi

Polymers (Basel). 2019 Oct 16;11(10):1696.

PMID: 31623193

Side-chain Crystallization in Alkyl-Substituted Cellulose Esters and Hydroxypropyl Cellulose Esters

Xi Chen, Nan Zheng, Qiao Wang, Lingzhi Liu, Yongfeng Men

Carbohydr Polym. 2017 Apr 15;162:28-34.

PMID: 28224891

* Products or Services Interested: Hydroxypropyl cellulose (9004-64-2)
* Your question
* Name
* Email
Verification Code

CAT	Size	Form	Description	Price
AP9004642-1	500MG	neat	United States Pharmacopeia (USP) Reference Standard	Inquiry
AP9004642-2	1G		Pharmaceutical Secondary Standard; Certified Reference Material	Inquiry
AP9004642-3	5G, 100G, 250G	powder	average Mw ~100,000, powder, 20 mesh particle size (99% through)	Inquiry

Case Study

Hydroxypropyl Cellulose Is Used for the Preparation of Geopolymeric Films with Enhanced Flame Retardancy and Thermal Stability

Bianco, Alessandro Lo, et al. Ceramics International (2025).

Hydroxypropyl cellulose (HPC), a water-soluble cellulose ether, is used for the preparation of geopolymeric films when combined with halloysite nanotubes (HNTs), offering a sustainable route to advanced fire-resistant materials. In this study, composite films containing 70 wt% HNTs and 30 wt% HPC were fabricated, then converted into geopolymeric structures via alkaline activation using 12 M NaOH, followed by thermal curing.
HPC plays a dual role-first as a binder and film-forming matrix, and second as a stabilizer for halloysite dispersion, preventing agglomeration by steric hindrance. The geopolymerization process imparts significant improvements in thermal resistance and mechanical integrity. Compared to the pristine HPC/HNT composite film, the resulting geopolymeric film (GP_HPC/HNTs) exhibits enhanced tensile strength and elevated thermal stability, as confirmed by thermogravimetric analysis.
Notably, the geopolymer demonstrates superior flame retardant behavior, completely halting flame propagation due to the formation of heat-resistant barrier layers. The incorporation of HNTs in the HPC matrix, even prior to geopolymerization, significantly reduces the burning rate (from 0.5 to 0.08 cm²/s), highlighting the synergistic flame-retardant effect of the nanotubes.
This work confirms that hydroxypropyl cellulose is effectively used for the preparation of fire-retardant geopolymeric films, offering a promising, eco-friendly alternative for high-performance applications in fire safety materials and thermal insulation systems.

Hydroxypropyl Cellulose Is Used for the Preparation of Thermochromic Hydrogels for Smart Window and Information Encryption Applications

Yi, Zhaodi, et al. Polymer (2025): 128717.

Hydroxypropyl cellulose (HPC), a thermoresponsive polysaccharide, is effectively used for the preparation of composite hydrogels with tunable thermochromic properties, enabling applications in smart windows and multi-level information encryption. In this study, HPC was incorporated into a polyacrylamide (PAM) hydrogel network alongside sodium carboxymethyl cellulose (CMC) via a one-pot free radical polymerization method. The integration of HPC imparts the hydrogel with temperature-sensitive optical switching behavior due to its inherent lower critical solution temperature (LCST) transition.
The resulting hydrogels display dual thermoresponsive behavior, with both upper (UCST) and lower (LCST) critical solution temperatures finely adjusted by varying CMC content. HPC serves as the key functional component, contributing to reversible phase transitions, transparency modulation, and optical responsiveness.
The hydrogel-based smart window achieved exceptional solar regulation (ΔT_{solar,25-40°C} = 80.81%) and infrared shielding, maintaining high visible light transmittance (T_lum ≈ 90.24%). Moreover, combining hydrogels with different transition temperatures enabled the creation of multi-layered QR code encryption systems and temperature-sensitive indicators.
This study demonstrates that hydroxypropyl cellulose is crucial for the preparation of advanced thermochromic hydrogels, offering an environmentally friendly, tunable, and scalable approach for smart material applications in energy-saving architecture and secure information display technologies.

Hydroxypropyl Cellulose Is Used for the Preparation of Electrically Conductive PAM-Based Hydrogels for Flexible Sensor and Catalytic Applications

Yi, Shurui, et al. International Journal of Biological Macromolecules 307 (2025): 141689.

Hydroxypropyl cellulose (HPC) is used as a key dispersant in the preparation of a multifunctional composite hydrogel (PAM-LMA-PDA@TiO₂-GN), which exhibits excellent mechanical, electrical, and catalytic properties. In this work, HPC was incorporated to enhance the dispersion stability of graphene within the hydrogel matrix, thereby promoting uniform conductivity and mechanical integration.
The hydrogel system was synthesized via free radical polymerization of acrylamide (AM) with lauryl methacrylate (LMA), forming a hydrophobic-associative network, while polydopamine-coated TiO₂ (PDA@TiO₂) nanoparticles were added to reinforce the structure. HPC significantly improved graphene dispersion and interaction within the network, ensuring efficient load transfer and electrical percolation. Ag nanowires (Ag NWs) and graphene further imparted high electrical conductivity and sensitivity (gauge factor = 10.46).
The resulting hydrogel showed remarkable strain tolerance (2519%) and compressive stress (1026 kPa), alongside fast electrical response (153 ms) and stable cyclic performance. Furthermore, the hydrogel demonstrated superior catalytic efficiency, with high degradation rate constants for Rhodamine B (k = 0.657 min⁻¹), methylene blue, and 4-nitrophenol, confirming its recyclability in catalytic reactions.
This study highlights hydroxypropyl cellulose as a crucial component for synthesizing graphene-based hydrogels with excellent flexibility, conductivity, and catalytic properties-ideal for next-generation wearable sensors and environmental remediation platforms.