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ICA-121431

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For Research Use Only | Not For Clinical Use
CATAP313254512
CAS313254-51-2
Molecular Weight449.55
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Characterization of Synthetic Tf2 as a Na V 1.3 Selective Pharmacological Probe

Mathilde R Israel, Thomas S Dash, Stefanie N Bothe, Samuel D Robinson, Jennifer R Deuis, David J Craik, Angelika Lampert, Irina Vetter, Thomas Durek

Biomedicines. 2020 Jun 11;8(6):E155.

PMID: 32545167

1

Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes

Jeremiah D Osteen, Kevin Sampson, Vivek Iyer, David Julius, Frank Bosmans

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6836-6841.

PMID: 28607094

1

Structure-Activity Relationship Evaluation of Wasp Toxin β-PMTX Leads to Analogs With Superior Activity for Human Neuronal Sodium Channels

Catherine E Garrison, Wendy Guan, Mitsunori Kato, Thomas Tamsett, Tajesh Patel, Yishan Sun, Tejas P Pathak

ACS Med Chem Lett. 2019 Oct 25;11(3):353-357.

PMID: 32184969

1

Voltage Sensor Interaction Site for Selective Small Molecule Inhibitors of Voltage-Gated Sodium Channels

Ken McCormack, Sonia Santos, Mark L Chapman, Douglas S Krafte, Brian E Marron, Christopher W West, Michael J Krambis, Brett M Antonio, Shannon G Zellmer, David Printzenhoff, Karen M Padilla, Zhixin Lin, etc.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):E2724-32.

PMID: 23818614

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