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Icilin

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For Research Use Only | Not For Clinical Use
CATIAR4243636
MDL NumberMFCD01689072
Molecular Weight311.29
InChI KeyRCEFMOGVOYEGJN-UHFFFAOYSA-N
Description≥97% (HPLC), solid
SolubilityDMSO: 15 mg/mL
Assay≥97% (HPLC)
Coloryellow
Formsolid
Size10MG, 50MG
1

Coordinated Targeting of Cold and Nicotinic Receptors Synergistically Improves Obesity and Type 2 Diabetes

Christoffer Clemmensen, Sigrid Jall, Maximilian Kleinert, Carmelo Quarta, Tim Gruber, Josefine Reber, Stephan Sachs, Katrin Fischer, Annette Feuchtinger, Angelos Karlas, Stephanie E Simonds, Gerald Grandl, etc.

Nat Commun. 2018 Oct 23;9(1):4304.

PMID: 30353008

1

Pharmacological Inhibition of TRPM8-induced Gene Transcription

Gerald Thiel, Tobias M Backes, Jennifer Welck, Sebastian Steinhausen, Anna-Lena Fischer, Daniel S Langfermann, Myriam Ulrich, Ulrich Wissenbach, Oliver G Rössler

Biochem Pharmacol. 2019 Dec;170:113678.

PMID: 31654626

1

Recent Progress in TRPM8 Modulation: An Update

Rosario González-Muñiz, M Angeles Bonache, Cristina Martín-Escura, Isabel Gómez-Monterrey

Int J Mol Sci. 2019 May 28;20(11):2618.

PMID: 31141957

1

Structural Basis of Cooling Agent and Lipid Sensing by the Cold-Activated TRPM8 Channel

Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee

Science. 2019 Mar 1;363(6430):eaav9334.

PMID: 30733385

1

The Cooling Compound Icilin Attenuates Autoimmune Neuroinflammation Through Modulation of the T-cell Response

Benjamin W Ewanchuk, Euan R O Allan, Amy L Warren, Rithwik Ramachandran, Robin M Yates

FASEB J. 2018 Mar;32(3):1236-1249.

PMID: 29114087

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