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IDRA 21

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For Research Use Only | Not For Clinical Use
CATAP22503726
CAS22503-72-6
Structure
MDL NumberMFCD00270874
Molecular Weight232.69
InChI KeyVZRNTCHTJRLTMU-UHFFFAOYSA-N
Description≥98%
Assay≥98%
Size5MG
1

7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 Benzothiadiazine S,S-dioxide (IDRA 21): A Benzothiadiazine Derivative That Enhances Cognition by Attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic Acid (AMPA) Receptor Desensitization

I Zivkovic, D M Thompson, M Bertolino, D Uzunov, M DiBella, E Costa, A Guidotti

J Pharmacol Exp Ther. 1995 Jan;272(1):300-9.

PMID: 7815345

1

IDRA-21, a Positive AMPA Receptor Modulator, Inhibits Synaptic and Extrasynaptic NMDA Receptor Mediated Events in Cultured Cerebellar Granule Cells

Gabriele Losi, Giulia Puia, Daniela Braghiroli, Mario Baraldi

Neuropharmacology. 2004 Jun;46(8):1105-13.

PMID: 15111017

1

The Diazoxide Derivative IDRA 21 Enhances Ischemic Hippocampal Neuron Injury

K A Yamada, D F Covey, C Y Hsu, R Hu, Y Hu, Y Y He

Ann Neurol. 1998 May;43(5):664-9.

PMID: 9585363

1

The Effects of Huperzine A and IDRA 21 on Visual Recognition Memory in Young Macaques

Ludise Malkova, Alan P Kozikowski, Karen Gale

Neuropharmacology. 2011 Jun;60(7-8):1262-8.

PMID: 21185313

1

The Effects of IDRA 21, a Positive Modulator of the AMPA Receptor, on Delayed Matching Performance by Young and Aged Rhesus Monkeys

Jerry J Buccafusco, Thomas Weiser, Karin Winter, Klaus Klinder, Alvin V Terry

Neuropharmacology. 2004 Jan;46(1):10-22.

PMID: 14654093

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