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Iguratimod

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For Research Use Only | Not For Clinical Use
CATAP123663490
CAS123663-49-0
Structure
MDL NumberMFCD00882374
Molecular Weight374.37
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Iguratimod Ameliorates Inflammatory Responses by Modulating the Th17/Treg Paradigm in Dextran Sulphate Sodium-Induced Murine Colitis

Xue-Pei Jiang, Xie-Lin Huang, Zao-Peng Yang, Shun-Cai Wang, Wei Xie, Lei Miao, Li Tang, Zhi-Ming Huang

Mol Immunol. 2018 Jan;93:9-19.

PMID: 29121519

1

Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes

Jin Lin, Ye Yu, Xuanwei Wang, Yini Ke, Chuanyin Sun, Lihuan Yue, Guanhua Xu, Bei Xu, Liqin Xu, Heng Cao, Danyi Xu, Nancy Olsen, Weiqian Chen

J Immunol Res. 2019 Nov 14;2019:6929286.

PMID: 31828173

1

Iguratimod Represses B Cell Terminal Differentiation Linked With the Inhibition of PKC/EGR1 Axis

Yan Ye, Mei Liu, Longhai Tang, Fang Du, Yuanhua Liu, Pei Hao, Qiong Fu, Qiang Guo, Qingran Yan, Xiaoming Zhang, Chunde Bao

Arthritis Res Ther. 2019 Apr 11;21(1):92.

PMID: 30971291

1

Investigation of the predictors of the response to Iguratimod therapy: A post-hoc analysis of post-marketing surveillance study

Naoki Ishiguro, Kai Shibata, Akiko Yoshimura, Satoshi Ikeuchi, Mika Ishii

Mod Rheumatol. 2019 Aug 8;1-7.

PMID: 31393189

1

Novel Disease-Modifying Anti-Rheumatic Drug Iguratimod Suppresses Chronic Experimental Autoimmune Encephalomyelitis by Down-Regulating Activation of macrophages/microglia Through an NF-κB Pathway

Guangrui Li, Ryo Yamasaki, Mei Fang, Katsuhisa Masaki, Hirofumi Ochi, Takuya Matsushita, Jun-Ichi Kira

Sci Rep. 2018 Jan 31;8(1):1933.

PMID: 29386552

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