CAS 36531-78-9 Ikarugamycin - Analytical Products / Alfa Chemistry

CAT	AP36531789
CAS	36531-78-9
Structure
Molecular Weight	478.62

Description	≥98% (HPLC), from Streptomyces sp.
Solubility	chloroform: 1 mg/mL (requires heating and sonication); methanol: 1 mg/mL (requires heating and sonication); DMSO: 5 mg/mL (requires heating and sonication); parasites
Assay	≥98% (HPLC)
Size	500UG
Storage Conditions	−20°C

1

Biocatalytic Total Synthesis of Ikarugamycin

Christian Greunke, Anna Glöckle, Janine Antosch, Tobias A M Gulder

Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4351-4355.

PMID: 28128495

1

Heterologous Reconstitution of Ikarugamycin Biosynthesis in E. Coli

Janine Antosch, Françoise Schaefers, Tobias A M Gulder

Angew Chem Int Ed Engl. 2014 Mar 10;53(11):3011-4.

PMID: 24519911

1

Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis

Sarah R Elkin, Nathaniel W Oswald, Dana K Reed, Marcel Mettlen, John B MacMillan, Sandra L Schmid

Traffic. 2016 Oct;17(10):1139-49.

PMID: 27392092

1

New Ikarugamycin Derivatives With Antifungal and Antibacterial Properties From Streptomyces Zhaozhouensis

Rodney Lacret, Daniel Oves-Costales, Cristina Gómez, Caridad Díaz, Mercedes de la Cruz, Ignacio Pérez-Victoria, Francisca Vicente, Olga Genilloud, Fernando Reyes

Mar Drugs. 2014 Dec 29;13(1):128-40.

PMID: 25551780

1

Small-molecule TFEB Pathway Agonists That Ameliorate Metabolic Syndrome in Mice and Extend C. Elegans Lifespan

Chensu Wang, Hanspeter Niederstrasser, Peter M Douglas, Rueyling Lin, Juan Jaramillo, Yang Li, Nathaniel W Oswald, Anwu Zhou, Elizabeth A McMillan, Saurabh Mendiratta, Zhaohui Wang, Tian Zhao, Zhiqaing Lin, etc.

Nat Commun. 2017 Dec 22;8(1):2270.

PMID: 29273768

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