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IL-12p40 human

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For Research Use Only | Not For Clinical Use
CATIAR4248651
Descriptionrecombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Assay≥98% (HPLC); ≥98% (SDS-PAGE)
Colorwhite to off-white
Formlyophilized
Impurity Content<0.1 EU/μg endotoxin, tested
Size10μG
Storage Conditions−20°C
1

IL-15 Negatively Regulates Curdlan-Induced IL-23 Production by Human Monocyte-Derived Dendritic Cells and Subsequent Th17 Response

Ahmet Eken, Zehra Okus, Serife Erdem, Zehra Busra Azizoglu, Yesim Haliloglu, Ayten Bicer, Tugba Nur Gur, Ebru Yilmaz, Musa Karakukcu, Hamiyet Donmez Altuntas, Halit Canatan

North Clin Istanb. 2019 Oct 24;6(4):379-387.

PMID: 31909384

1

Neutrophil Elastase Enhances IL-12p40 Production by Lipopolysaccharide-Stimulated Macrophages via Transactivation of the PAR-2/EGFR/TLR4 Signaling Pathway

Rui Yamaguchi, Takatoshi Yamamoto, Arisa Sakamoto, Shinji Narahara, Hiroyuki Sugiuchi, Yasuo Yamaguchi

Blood Cells Mol Dis. 2016 Jul;59:1-7.

PMID: 27282560

1

Regulation of IL-12p40 by HIF Controls Th1/Th17 Responses to Prevent Mucosal Inflammation

E Marks, C Naudin, G Nolan, B J Goggins, G Burns, S W Mateer, J K Latimore, K Minahan, M Plank, P S Foster, R Callister, M Veysey, M M Walker, N J Talley, G Radford-Smith, S Keely

Mucosal Immunol. 2017 Sep;10(5):1224-1236.

PMID: 28120851

1

Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1

Yehudi Bloch, Laura Bouchareychas, Romain Merceron, Katarzyna Składanowska, Lien Van den Bossche, Sammy Detry, Srinath Govindarajan, Dirk Elewaut, Filomeen Haerynck, Melissa Dullaers, Iannis E Adamopoulos, etc.

Immunity. 2018 Jan 16;48(1):45-58.e6.

PMID: 29287995

1

Suppression of IL-12p40-related Regulatory Cytokines by Suberoylanilide Hydroxamic Acid an Inhibitor of Histone Deacetylases

Zlatka Georgieva Dobreva, Boncho Grigorov Grigorov, Spaska Angelova Stanilova

Immunopharmacol Immunotoxicol. 2016 Aug;38(4):281-5.

PMID: 27240992

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