IL-17F human - Analytical Products / Alfa Chemistry

CAT

IAR42413364

Description	recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Assay	≥98% (HPLC); ≥98% (SDS-PAGE)
Form	lyophilized
Impurity Content	endotoxin, tested
Size	25μG
Storage Conditions	−20°C

1

Dual IL-17A and IL-17F Neutralisation by Bimekizumab in Psoriatic Arthritis: Evidence From Preclinical Experiments and a Randomised Placebo-Controlled Clinical Trial That IL-17F Contributes to Human Chronic Tissue Inflammation

Sophie Glatt, Dominique Baeten, Terry Baker, Meryn Griffiths, Lucian Ionescu, Alastair D G Lawson, Ash Maroof, Ruth Oliver, Serghei Popa, Foteini Strimenopoulou, Pavan Vajjah, Mark I L Watling, Nataliya Yeremenko, etc.

Ann Rheum Dis. 2018 Apr;77(4):523-532.

PMID: 29275332

1

Effects of the IL-23-IL-17 Pathway on Bone in Spondyloarthritis

Ellen M Gravallese, Georg Schett

Nat Rev Rheumatol. 2018 Nov;14(11):631-640.

PMID: 30266977

1

First-in-human Randomized Study of Bimekizumab, a Humanized Monoclonal Antibody and Selective Dual Inhibitor of IL-17A and IL-17F, in Mild Psoriasis

Sophie Glatt, Eric Helmer, Birgit Haier, Foteini Strimenopoulou, Graham Price, Pavan Vajjah, Olivier A Harari, John Lambert, Stevan Shaw

Br J Clin Pharmacol. 2017 May;83(5):991-1001.

PMID: 27859546

1

IL-12, IL-23 and IL-17 in IBD: Immunobiology and Therapeutic Targeting

Alexander R Moschen, Herbert Tilg, Tim Raine

Nat Rev Gastroenterol Hepatol. 2019 Mar;16(3):185-196.

PMID: 30478416

1

IL-17F Regulates Psoriasis-Associated Genes Through IκBζ

Trine Bertelsen, Christine Ljungberg, Rasmus Boye Kjellerup, Lars Iversen, Claus Johansen

Exp Dermatol. 2017 Mar;26(3):234-241.

PMID: 27576147

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