IL-2 (human): FC (human) - Analytical Products / Alfa Chemistry

CAT

IAR42413378

Description	recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
Assay	>95% (SDS-PAGE)
Color	white
Form	lyophilized
Impurity Content	<0.01 EU/μg endotoxin, tested
Size	10μG
Storage Conditions	−20°C

1

A Recombinant anti-erbB2, scFv-Fc-IL-2 Fusion Protein Retains Antigen Specificity and Cytokine Function

Ming Shi, Zhigang Xie, Jiannan Feng, Yingxun Sun, Ming Yu, Beifen Shen, Ning Guo

Biotechnol Lett. 2003 May;25(10):815-9.

PMID: 12882013

1

An anti-CD20-IL-2 Immunocytokine Is Highly Efficacious in a SCID Mouse Model of Established Human B Lymphoma

Stephen D Gillies, Yan Lan, Steven Williams, Frank Carr, Stephen Forman, Andrew Raubitschek, Kin-Ming Lo

Blood. 2005 May 15;105(10):3972-8.

PMID: 15692062

1

Antibody-dependent Cell Cytotoxicity: Immunotherapy Strategies Enhancing Effector NK Cells

Maria Carmen Ochoa, Luna Minute, Inmaculada Rodriguez, Saray Garasa, Elisabeth Perez-Ruiz, Susana Inogés, Ignacio Melero, Pedro Berraondo

Immunol Cell Biol. 2017 Apr;95(4):347-355.

PMID: 28138156

1

Anti-CD30-scFv-Fc-IL-2 Antibody-Cytokine Fusion Protein That Induces Resting NK Cells to Highly Efficient Cytolysis of Hodgkin's Lymphoma Derived Tumour Cells

Claudia Heuser, Stefan Guhlke, Alexander Matthies, Hans Bender, Stefan Barth, Volker Diehl, Hinrich Abken, Andreas Hombach

Int J Cancer. 2004 Jun 20;110(3):386-94.

PMID: 15095304

1

Cergutuzumab Amunaleukin (CEA-IL2v), a CEA-targeted IL-2 Variant-Based Immunocytokine for Combination Cancer Immunotherapy: Overcoming Limitations of Aldesleukin and Conventional IL-2-based Immunocytokines

Christian Klein, Inja Waldhauer, Valeria G Nicolini, Anne Freimoser-Grundschober, Tapan Nayak, Danielle J Vugts, Claire Dunn, Marije Bolijn, Jörg Benz, Martine Stihle, Sabine Lang, Michaele Roemmele, Thomas Hofer, etc.

Oncoimmunology. 2017 Jan 11;6(3):e1277306.

PMID: 28405498

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