CAS 978-62-1 IMD-0354 - Analytical Products / Alfa Chemistry

CAT	AP978621
CAS	978-62-1
MDL Number	MFCD00218820
Molecular Weight	383.67
InChI Key	CHILCFMQWMQVAL-UHFFFAOYSA-N

Description	≥98% (HPLC), solid
Solubility	DMSO: >20 mg/mL
Assay	≥98% (HPLC)
Form	solid
Size	5MG, 10MG
Storage Conditions	−20°C

1

IKK β Inhibitor IMD-0354 Attenuates Radiation Damage in Whole-body X-Irradiated Mice

Kengo Waga, Masaru Yamaguchi, Shuta Miura, Teruki Nishida, Akiko Itai, Reiko Nakanishi, Ikuo Kashiwakura

Oxid Med Cell Longev. 2019 Nov 27;2019:5340290.

PMID: 31885799

1

IκB Kinase β Inhibitor, IMD-0354, Prevents Allergic Asthma in a Mouse Model Through Inhibition of CD4(+) Effector T Cell Responses in the Lung-Draining Mediastinal Lymph Nodes

Tomasz Maślanka, Iwona Otrocka-Domagała, Monika Zuśka-Prot, Mateusz Mikiewicz, Jagoda Przybysz, Agnieszka Jasiecka, Jerzy J Jaroszewski

Eur J Pharmacol. 2016 Mar 15;775:78-85.

PMID: 26868187

1

IκB kinase-β Inhibitor IMD-0354 Beneficially Suppresses Retinal Vascular Permeability in Streptozotocin-Induced Diabetic Mice

Anton Lennikov, Miki Hiraoka, Akira Abe, Shigeaki Ohno, Tomoyuki Fujikawa, Akiko Itai, Hiroshi Ohguro

Invest Ophthalmol Vis Sci. 2014 Sep 9;55(10):6365-73.

PMID: 25205865

1

The Emerging Role of IMD 0354 on Bone Homeostasis by Suppressing Osteoclastogenesis and Bone Resorption, but Without Affecting Bone Formation

Wenxiang Chen, Ziang Xie, Pan Tang, Yongli Wang, Zhiwei Jie, An Qin, Xuesheng Jiang, Zhijun Hu, Shunwu Fan

Cell Death Dis. 2019 Sep 10;10(9):654.

PMID: 31506437

1

The NF-κB Inhibitor, IMD-0354, Affects Immune Gene Expression, Bacterial Microbiota and Trypanosoma cruzi Infection in Rhodnius prolixus Midgut

Cecilia S Vieira, Otacílio C Moreira, Kate K S Batista, Norman A Ratcliffe, Daniele P Castro, Patrícia Azambuja

Front Physiol. 2018 Aug 31;9:1189.

PMID: 30233391

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