CAS 160807-49-8 Indirubin-3′-oxime - Analytical Products / Alfa Chemistry

CAT	AP160807498-A
CAS	160807-49-8
Structure
MDL Number	MFCD02683594
Molecular Weight	277.28
InChI Key	HBDSHCUSXQATPO-BGBJRWHRSA-N

Description	≥98% (HPLC), solid
Solubility	DMSO: >10 mg/mL; H2O: insoluble
Assay	≥98% (HPLC)
Form	solid
Size	1MG, 5MG

1

Indirubin 3'-oxime Inhibits Anticancer Agent-Induced YB-1 Nuclear Translocation in HepG2 Human Hepatocellular Carcinoma Cells

Toru Tanaka, Sachiyo Ohashi, Hiroaki Saito, Taira Wada, Tadashi Aoyama, Yoshimi Ichimaru, Shinichi Miyairi, Shunsuke Kobayashi

Biochem Biophys Res Commun. 2018 Jan 29;496(1):7-11.

PMID: 29274785

1

Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of GSK3β

Shengquan Hu, Wei Cui, Zaijun Zhang, Shinghung Mak, Daping Xu, Gang Li, Yuanjia Hu, Yuqiang Wang, Mingyuen Lee, Karl Wahkeung Tsim, Yifan Han

J Mol Neurosci. 2015 Dec;57(4):561-70.

PMID: 26346600

1

Indirubin-3'-oxime Impairs Mitochondrial Oxidative Phosphorylation and Prevents Mitochondrial Permeability Transition Induction

Ana T Varela, Ana P Gomes, Anabela M Simões, João S Teodoro, Filipe V Duarte, Anabela P Rolo, Carlos M Palmeira

Toxicol Appl Pharmacol. 2008 Dec 1;233(2):179-85.

PMID: 18786556

1

Indirubin-3-Oxime Prevents H 2 O 2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway

Jie Yu, Jiacheng Zheng, Jiajia Lin, Linlu Jin, Rui Yu, Shinghung Mak, Shengquan Hu, Hongya Sun, Xiang Wu, Zaijun Zhang, Mingyuen Lee, Wahkeung Tsim, Wei Su, Wenhua Zhou, Wei Cui, Yifan Han, Qinwen Wang

Cell Mol Neurobiol. 2017 May;37(4):655-664.

PMID: 27412761

1

Indirubin-3'-oxime Prevents Hepatic I/R Damage by Inhibiting GSK-3beta and Mitochondrial Permeability Transition

Ana T Varela, Anabela M Simões, João S Teodoro, Filipe V Duarte, Ana P Gomes, Carlos M Palmeira, Anabela P Rolo

Mitochondrion. 2010 Aug;10(5):456-63.

PMID: 20433952

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