CAS 75567-37-2 Ingenol-3-angelate - Analytical Products / Alfa Chemistry

CAT	AP75567372
CAS	75567-37-2
Structure
Molecular Weight	430.53
InChI Key	VDJHFHXMUKFKET-WDUFCVPESA-N

Description	≥95% (HPLC)
Solubility	DMSO: 15 mg/mL, clear
Assay	≥95% (HPLC)
Color	white to beige
Form	powder
Size	1MG
Storage Conditions	−20°C

1

Characterization of the Interaction of Ingenol 3-angelate With Protein Kinase C

Noemi Kedei, Daniel J Lundberg, Attila Toth, Peter Welburn, Susan H Garfield, Peter M Blumberg

Cancer Res. 2004 May 1;64(9):3243-55.

PMID: 15126366

1

Immunostimulatory Cancer Chemotherapy Using Local ingenol-3-angelate and Synergy With Immunotherapies

Thuy T T Le, Joy Gardner, Diem Hoang-Le, Chris W Schmidt, Kelli P MacDonald, Eleanore Lambley, Wayne A Schroder, Steven M Ogbourne, Andreas Suhrbier

Vaccine. 2009 May 18;27(23):3053-62.

PMID: 19428919

1

Ingenol 3-angelate Induces Dual Modes of Cell Death and Differentially Regulates Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Melanoma Cells

Susan K Gillespie, Xu Dong Zhang, Peter Hersey

Mol Cancer Ther. 2004 Dec;3(12):1651-8.

PMID: 15634659

1

Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling

Dunwei Wang, Pengcheng Liu

Med Sci Monit. 2018 Jan 25;24:486-502.

PMID: 29368698

1

Novel Antileukemic Compound Ingenol 3-angelate Inhibits T Cell Apoptosis by Activating Protein Kinase Ctheta

Wing-Yiu Lee, Peter Hampson, Lydia Coulthard, Farrah Ali, Mike Salmon, Janet M Lord, Dagmar Scheel-Toellner

J Biol Chem. 2010 Jul 30;285(31):23889-98.

PMID: 20472553

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