CAS 5852-78-8 IOX1 - Analytical Products / Alfa Chemistry

CAT	AP5852788
CAS	5852-78-8
MDL Number	MFCD18417145
Molecular Weight	189.17
InChI Key	JGRPKOGHYBAVMW-UHFFFAOYSA-N

Description	≥97% (HPLC)
Solubility	DMSO: 10 mg/mL, clear
Assay	≥97% (HPLC)
Color	white to brown
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

5-Carboxy-8-hydroxyquinoline Is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor Which Causes Iron Translocation

Richard J Hopkinson, Anthony Tumber, Clarence Yapp, Rasheduzzaman Chowdhury, WeiShen Aik, Ka Hing Che, Xuan Shirley Li, Jan B L Kristensen, Oliver N F King, Mun Chiang Chan, Kar Kheng Yeoh, Hwanho Choi, etc.

Chem Sci. 2013 Aug 1;4(8):3110-3117.

PMID: 26682036

1

IOX1, a JMJD2A Inhibitor, Suppresses the Proliferation and Migration of Vascular Smooth Muscle Cells Induced by Angiotensin II by Regulating the Expression of Cell Cycle-Related Proteins

Qi Hu, Jing Chen, Jing Zhang, Changwu Xu, Shuo Yang, Hong Jiang

Int J Mol Med. 2016 Jan;37(1):189-96.

PMID: 26530537

1

Radiation-Induced CXCL12 Upregulation via Histone Modification at the Promoter in the Tumor Microenvironment of Hepatocellular Carcinoma

Hak Jun Ahn, Soon Young Hwang, Ngoc Hoan Nguyen, Ik Jae Lee, Eun Jeong Lee, Jinsil Seong, Jong-Soo Lee

Mol Cells. 2019 Jul 15;42(6):502.

PMID: 31304690

1

Selective Silencing of α-globin by the Histone Demethylase Inhibitor IOX1: A Potentially New Pathway for Treatment of β-thalassemia

Sachith Mettananda, Christopher A Fisher, Jackie A Sloane-Stanley, Stephen Taylor, Udo Oppermann, Richard J Gibbons, Douglas R Higgs

Haematologica. 2017 Mar;102(3):e80-e84.

PMID: 27810991

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