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IPA-3

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For Research Use Only | Not For Clinical Use
CATAP42521824
CAS42521-82-4
Structure
MDL NumberMFCD00388917
Molecular Weight350.45
InChI KeyRFAXLXKIAKIUDT-UHFFFAOYSA-N
Description≥95% (HPLC), powder
SolubilityDMSO: >20 mg/mL; H2O: insoluble
Assay≥95% (HPLC)
Coloroff-white to yellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Effect of P21-activated Kinase 1 (PAK-1) Inhibition on Cancer Cell Growth, Migration, and Invasion

Wided Najahi-Missaoui, Nhat D Quach, Amber Jenkins, Isha Dabke, Payaningal R Somanath, Brian S Cummings

Pharmacol Res Perspect. 2019 Sep 6;7(5):e00518.

PMID: 31516713

1

Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells

Kateřina Kuželová, Dana Grebeňová, Aleš Holoubek, Pavla Röselová, Adam Obr

PLoS One. 2014 Mar 24;9(3):e92560.

PMID: 24664099

1

Inhibition of p21-Activated Kinase 1 by IPA-3 Promotes Locomotor Recovery After Spinal Cord Injury in Mice

Xinran Ji, Yiling Zhang, Lihai Zhang, Hua Chen, Ye Peng, Peifu Tang

Spine (Phila Pa 1976). 2016 Jun;41(11):919-25.

PMID: 26863260

1

IPA-3 Inhibits the Growth of Liver Cancer Cells by Suppressing PAK1 and NF-κB Activation

Leo Lap-Yan Wong, Ian Pak-Yan Lam, Tracy Yuk-Nar Wong, Wai-Lung Lai, Heong-Fai Liu, Lam-Lung Yeung, Yick-Pang Ching

PLoS One. 2013 Jul 19;8(7):e68843.

PMID: 23894351

1

Liposome-mediated Delivery of the p21 Activated kinase-1 (PAK-1) Inhibitor IPA-3 Limits Prostate Tumor Growth in Vivo

Ahmad Al-Azayzih, Wided N Missaoui, Brian S Cummings, Payaningal R Somanath

Nanomedicine. 2016 Jul;12(5):1231-1239.

PMID: 26949163

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