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Iperoxo

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For Research Use Only | Not For Clinical Use
CATAP247079841
CAS247079-84-1
Molecular Weight324.16
Description≥98% (HPLC)
SolubilityH2O: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Activation and Allosteric Modulation of a Muscarinic Acetylcholine Receptor

Andrew C Kruse, Aaron M Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Celine Valant, Patrick M Sexton, Arthur Christopoulos, Christian C Felder, Peter Gmeiner, Jan Steyaert, etc.

Nature. 2013 Dec 5;504(7478):101-6.

PMID: 24256733

1

Agonists With Supraphysiological Efficacy at the Muscarinic M2 ACh Receptor

R Schrage, W K Seemann, J Klöckner, C Dallanoce, K Racké, E Kostenis, M De Amici, U Holzgrabe, K Mohr

Br J Pharmacol. 2013 May;169(2):357-70.

PMID: 23062057

1

N-Ethylmaleimide differentiates between the M 2- and M 4-autoreceptor-mediated inhibition of acetylcholine release in the mouse brain

Justine Etscheid, Klaus Mohr, Eberhard Schlicker

Naunyn Schmiedebergs Arch Pharmacol. 2018 Nov;391(11):1295-1299.

PMID: 30032313

1

New Insight Into Active Muscarinic Receptors With the Novel Radioagonist [³H]iperoxo

Ramona Schrage, Janine Holze, Jessica Klöckner, Aileen Balkow, Anne S Klause, Anna-Lena Schmitz, Marco De Amici, Evi Kostenis, Christian Tränkle, Ulrike Holzgrabe, Klaus Mohr

Biochem Pharmacol. 2014 Aug 1;90(3):307-19.

PMID: 24863257

1

Rational Design of Partial Agonists for the Muscarinic m1 Acetylcholine Receptor

Xinyu Chen, Jessika Klöckner, Janine Holze, Cornelia Zimmermann, Wiebke K Seemann, Ramona Schrage, Andreas Bock, Klaus Mohr, Christian Tränkle, Ulrike Holzgrabe, Michael Decker

J Med Chem. 2015 Jan 22;58(2):560-76.

PMID: 25478907

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