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IQ-1S

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For Research Use Only | Not For Clinical Use
CATALP23146227
CAS23146-22-7 (free acid)
Molecular Weight269.23
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Novel Dual NO-donating Oxime and c-Jun N-terminal Kinase Inhibitor Protects Against Cerebral Ischemia-Reperfusion Injury in Mice

Dmitriy N Atochin, Igor A Schepetkin, Andrei I Khlebnikov, Victor I Seledtsov, Helen Swanson, Mark T Quinn, Paul L Huang

Neurosci Lett. 2016 Apr 8;618:45-49.

PMID: 26923672

1

Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis After Treatment With IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor

Igor A Schepetkin, Liliya N Kirpotina, Deepa Hammaker, Irina Kochetkova, Andrei I Khlebnikov, Sergey A Lyakhov, Gary S Firestein, Mark T Quinn

J Pharmacol Exp Ther. 2015 Jun;353(3):505-16.

PMID: 25784649

1

c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury

Maria Shvedova, Yana Anfinogenova, Elena N Atochina-Vasserman, Igor A Schepetkin, Dmitriy N Atochin

Front Pharmacol. 2018 Jul 5;9:715.

PMID: 30026697

1

Inhibitory Effect of IQ-1S, a Selective c-Jun N-terminal Kinase (JNK) Inhibitor, on Phenotypical and Cytokine-Producing Characteristics in Human Macrophages and T-cells

Victor I Seledtsov, Vladimir V Malashchenko, Maksim E Meniailo, Dmitriy N Atochin, Galina V Seledtsova, Igor A Schepetkin

Eur J Pharmacol. 2020 Jul 5;878:173116.

PMID: 32315671

1

Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats

Mark B Plotnikov, Galina A Chernysheva, Oleg I Aliev, Vera I Smol'iakova, Tatiana I Fomina, Anton N Osipenko, Victoria S Rydchenko, Yana J Anfinogenova, Andrei I Khlebnikov, Igor A Schepetkin, Dmitriy N Atochin

Molecules. 2019 May 3;24(9):1722.

PMID: 31058815

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