CAS 9028-48-2 Isocitrate Dehydrogenase 1 (NADP+) human - Analytical Products / Alfa Chemistry

CAT	AP9028482-B
CAS	9028-48-2

Description	recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE)
Assay	≥0.30 mg/mL protein basis (Bradford); ≥90% (SDS-PAGE)
Form	buffered aqueous glycerol solution
Size	10μG
Storage Conditions	−70°C

1

Inhibitor Potency Varies Widely Among Tumor-Relevant Human Isocitrate Dehydrogenase 1 Mutants

Diego Avellaneda Matteo, Grace A Wells, Lucas A Luna, Adam J Grunseth, Olga Zagnitko, David A Scott, An Hoang, Amit Luthra, Manal A Swairjo, Jamie M Schiffer, Christal D Sohl

Biochem J. 2018 Oct 22;475(20):3221-3238.

PMID: 30249606

1

Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

Zachary J Reitman, Hai Yan

J Natl Cancer Inst. 2010 Jul 7;102(13):932-41.

PMID: 20513808

1

Mitochondrial Isocitrate Dehydrogenase Protects Human Neuroblastoma SH-SY5Y Cells Against Oxidative Stress

Sun J Kim, Tae Y Yune, Ching T Han, Young C Kim, Young J Oh, George J Markelonis, Tae H Oh

J Neurosci Res. 2007 Jan;85(1):139-52.

PMID: 17075901

1

Mitochondrial NADP+-dependent Isocitrate Dehydrogenase Protects Cadmium-Induced Apoptosis

In Sup Kil, Seoung Woo Shin, Hyun Seok Yeo, Young Sup Lee, Jeen-Woo Park

Mol Pharmacol. 2006 Sep;70(3):1053-61.

PMID: 16785314

1

Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States

Joseph V Roman, Trevor R Melkonian, Nicholas R Silvaggi, Graham R Moran

Biochemistry. 2019 Dec 31;58(52):5366-5380.

PMID: 31478653

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