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Isosilybin A

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For Research Use Only | Not For Clinical Use
CATAP142796212
CAS142796-21-2
Molecular Weight482.44
Descriptionanalytical standard
Assay≥95.0% (HPLC)
Formneat; gas chromatography (GC): suitable
Gradeanalytical standard
Impurity Content≤10.0% water
Size5MG
1

A Biomimetic Strategy to Access the Silybins: Total Synthesis of (-)-Isosilybin A

Benjamin R McDonald, Antoinette E Nibbs, Karl A Scheidt

Org Lett. 2015 Jan 2;17(1):98-101.

PMID: 25517432

1

Identification of Isosilybin a From Milk Thistle Seeds as an Agonist of Peroxisome Proliferator-Activated Receptor Gamma

Eva-Maria Pferschy-Wenzig, Atanas G Atanasov, Clemens Malainer, Stefan M Noha, Olaf Kunert, Daniela Schuster, Elke H Heiss, Nicholas H Oberlies, Hildebert Wagner, Rudolf Bauer, Verena M Dirsch

J Nat Prod. 2014 Apr 25;77(4):842-7.

PMID: 24597776

1

Isosilybin A Induces Apoptosis in Human Prostate Cancer Cells via Targeting Akt, NF-κB, and Androgen Receptor Signaling

Gagan Deep, Subhash C Gangar, Nicholas H Oberlies, David J Kroll, Rajesh Agarwal

Mol Carcinog. 2010 Oct;49(10):902-12.

PMID: 20721970

1

Isosilybin B and Isosilybin A Inhibit Growth, Induce G1 Arrest and Cause Apoptosis in Human Prostate Cancer LNCaP and 22Rv1 Cells

Gagan Deep, Nicholas H Oberlies, David J Kroll, Rajesh Agarwal

Carcinogenesis. 2007 Jul;28(7):1533-42.

PMID: 17389612

1

The Effect of Milk Thistle (Silybum Marianum) and Its Main Flavonolignans on CYP2C8 Enzyme Activity in Human Liver Microsomes

Ahmed A Albassam, Reginald F Frye, John S Markowitz

Chem Biol Interact. 2017 Jun 1;271:24-29.

PMID: 28457856

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