CAS 457081-03-7 JAK Inhibitor I - CAS 457081-03-7 - Analytical Products / Alfa Chemistry

Description	JAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC₅₀ = 15 nM), JAK2 (IC₅₀ = 1 nM), JAK3 (Ki = 5 nM) and Tyk2 (IC₅₀ = 1 nM).
Solubility	DMSO: 5 mg/mL
Assay	≥98% (HPLC)
Color	off-white
Form	solid; protect from light
Size	500μG, 1MG
Storage Conditions	-20C

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1

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J Leukoc Biol. 2018 Oct;104(4):799-809.

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