JAK Inhibitor I - CAS 457081-03-7

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For Research Use Only | Not For Clinical Use
CATAP457081037-B
CAS457081-03-7
Structure
Molecular Weight309.34
DescriptionJAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC₅₀ = 15 nM), JAK2 (IC₅₀ = 1 nM), JAK3 (Ki = 5 nM) and Tyk2 (IC₅₀ = 1 nM).
SolubilityDMSO: 5 mg/mL
Assay≥98% (HPLC)
Coloroff-white
Formsolid; protect from light
Size500μG, 1MG
Storage Conditions-20C
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