CAS 202475-60-3 JAK3 Inhibitor I - CAS 202475-60-3 - Analytical Products / Alfa Chemistry

CAT	AP202475603
CAS	202475-60-3
Structure
Molecular Weight	297.31

Description	The JAK3 Inhibitor I, also referenced under CAS 202475-60-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Solubility	DMSO: 50 mg/mL
Assay	≥97% (HPLC)
Color	white to off-white
Form	solid; protect from light
Size	5MG
Storage Conditions	-20C

1

Effect of Targeting Janus Kinase 3 on the Development of Intestinal Tumors in the Adenomatous Polyposis Coli(min) Mouse Model of Familial Adenomatous Polyposis

Fatih M Uckun, Douglas Erbeck, Sanjive Qazi, Taracad Venkatachalam, Heather E Tibbles, Alexei Vassilev

Arzneimittelforschung. 2007;57(6):320-9.

PMID: 17688077

1

Prevention of Islet Allograft Rejection in Diabetic Mice by Targeting Janus Kinase 3 With 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline (JANEX-1)

Marina Cetkovic-Cvrlje, Angela L Dragt, Fatih M Uckun

Arzneimittelforschung. 2003;53(9):648-54.

PMID: 14558439

1

Prevention of UVB-induced Skin Inflammation, Genotoxicity, and Photocarcinogenesis in Mice by WHI-P131, a Dual-Function Inhibitor of Janus Kinase 3 and EGF Receptor Kinase

Fatih M Uckun, Ilker Dibirdik, Sanjive Qazi

Arzneimittelforschung. 2010;60(4):218-25.

PMID: 20486473

1

Therapeutic Nanoparticle Constructs of a JAK3 Tyrosine Kinase Inhibitor Against Human B-lineage ALL Cells

Fatih M Uckun, Ilker Dibirdik, Sanjive Qazi, Seang Yiv

Arzneimittelforschung. 2010;60(4):210-7.

PMID: 20486472

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