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Jasplakinolide

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For Research Use Only | Not For Clinical Use
CATAP102396247
CAS102396-24-7
Structure
MDL NumberMFCD00873735
Molecular Weight709.67
InChI KeyGQWYWHOHRVVHAP-DHKPLNAMSA-N
Description≥97% (HPLC)
SolubilityDMSO: >2 mg/mL
Assay≥97% (HPLC)
Coloroff-white to beige
Formfilm (colorless)
Size100UG
Storage Conditions−20°C
1

Actin Stabilizing Compounds Show Specific Biological Effects Due to Their Binding Mode

Shuaijun Wang, Alvaro H Crevenna, Ilke Ugur, Antoine Marion, Iris Antes, Uli Kazmaier, Maria Hoyer, Don C Lamb, Florian Gegenfurtner, Zane Kliesmete, Christoph Ziegenhain, Wolfgang Enard, Angelika Vollmar, etc.

Sci Rep. 2019 Jul 5;9(1):9731.

PMID: 31278311

1

Assembly and Maintenance of Myofibrils in Striated Muscle

Joseph W Sanger, Jushuo Wang, Yingli Fan, Jennifer White, Lei Mi-Mi, Dipak K Dube, Jean M Sanger, David Pruyne

Handb Exp Pharmacol. 2017;235:39-75.

PMID: 27832381

1

Aβ Mediates F-actin Disassembly in Dendritic Spines Leading to Cognitive Deficits in Alzheimer's Disease

Reddy Peera Kommaddi, Debajyoti Das, Smitha Karunakaran, Siddharth Nanguneri, Deepti Bapat, Ajit Ray, Eisha Shaw, David A Bennett, Deepak Nair, Vijayalakshmi Ravindranath

J Neurosci. 2018 Jan 31;38(5):1085-1099.

PMID: 29246925

1

Jasplakinolide, a Cytotoxic Natural Product, Induces Actin Polymerization and Competitively Inhibits the Binding of Phalloidin to F-actin

M R Bubb, A M Senderowicz, E A Sausville, K L Duncan, E D Korn

J Biol Chem. 1994 May 27;269(21):14869-71.

PMID: 8195116

1

The Role of Palladin in Podocytes

Nadine Artelt, Tim A Ludwig, Henrik Rogge, Panagiotis Kavvadas, Florian Siegerist, Antje Blumenthal, Jens van den Brandt, Carol A Otey, Marie-Louise Bang, Kerstin Amann, Christos E Chadjichristos, Christos Chatziantoniou, etc.

J Am Soc Nephrol. 2018 Jun;29(6):1662-1678.

PMID: 29720549

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