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JNJ-40418677

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For Research Use Only | Not For Clinical Use
CATAP1146594877
CAS1146594-87-7
Molecular Weight480.44
Description≥98% (HPLC)
SolubilityDMSO: 15 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Chronic Treatment With a Novel γ-secretase Modulator, JNJ-40418677, Inhibits Amyloid Plaque Formation in a Mouse Model of Alzheimer's Disease

B Van Broeck, J-M Chen, G Tréton, M Desmidt, C Hopf, N Ramsden, E Karran, M Mercken, A Rowley

Br J Pharmacol. 2011 May;163(2):375-89.

PMID: 21232036

1

Iridium-catalyzed Enantioselective Allyl-Alkene Coupling

James Y Hamilton, David Sarlah, Erick M Carreira

J Am Chem Soc. 2014 Feb 26;136(8):3006-9.

PMID: 24521052

1

Potential Novel Targets for Alzheimer Pharmacotherapy: II. Update on Secretase Inhibitors and Related Approaches

J A Mikulca, V Nguyen, D A Gajdosik, S G Teklu, E A Giunta, E A Lessa, C H Tran, E C Terak, R B Raffa

J Clin Pharm Ther. 2014 Feb;39(1):25-37.

PMID: 24313554

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