CAS 1410880-22-6 JNK-IN-8 - Analytical Products / Alfa Chemistry

CAT	AP1410880226-B
CAS	1410880-22-6
MDL Number	MFCD22124890
Molecular Weight	507.59
InChI Key	GJFCSAPFHAXMSF-UHFFFAOYSA-N

Description	≥96% (HPLC)
Solubility	DMSO: 20 mg/mL, clear
Assay	≥96% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

A c-Jun N-terminal Kinase Inhibitor, JNK-IN-8, Sensitizes Triple Negative Breast Cancer Cells to Lapatinib

Nancy D Ebelt, Tamer S Kaoud, Ramakrishna Edupuganti, Sabrina Van Ravenstein, Kevin N Dalby, Carla L Van Den Berg

Oncotarget. 2017 Aug 24;8(62):104894-104912.

PMID: 29285221

1

Activation of AMPK Inhibits Inflammatory Response During Hypoxia and Reoxygenation Through Modulating JNK-mediated NF-κB Pathway

Xu Chen, Xuan Li, Wenyan Zhang, Jie He, Bo Xu, Bin Lei, Zhenhua Wang, Courtney Cates, Thomas Rousselle, Ji Li

Metabolism. 2018 Jun;83:256-270.

PMID: 29526538

1

Irreversible JNK1-JUN Inhibition by JNK-IN-8 Sensitizes Pancreatic Cancer to 5-FU/FOLFOX Chemotherapy

Matthew B Lipner, Xianlu L Peng, Chong Jin, Yi Xu, Yanzhe Gao, Michael P East, Naim U Rashid, Richard A Moffitt, Silvia G Herrera Loeza, Ashley B Morrison, Brian T Golitz, Cyrus Vaziri, Lee M Graves, Gary L Johnson, etc.

JCI Insight. 2020 Apr 23;5(8):e129905.

PMID: 32213714

1

JNK2 Is Required for the Tumorigenic Properties of Melanoma Cells

Lili Du, Anna Anderson, Kimberly Nguyen, Sandra S Ojeda, Ivannie Ortiz-Rivera, Tran Ngoc Nguyen, Tinghu Zhang, Tamer S Kaoud, Nathanael S Gray, Kevin N Dalby, Kenneth Y Tsai

ACS Chem Biol. 2019 Jul 19;14(7):1426-1435.

PMID: 31063355

1

JNK-IN-8, a c-Jun N-terminal Kinase Inhibitor, Improves Functional Recovery Through Suppressing Neuroinflammation in Ischemic Stroke

Jianjian Zheng, Qinxue Dai, Kunyuan Han, Wandong Hong, Danyun Jia, Yunchang Mo, Ya Lv, Hongli Tang, Hongxing Fu, Wujun Geng

J Cell Physiol. 2020 Mar;235(3):2792-2799.

PMID: 31541462

* Products or Services Interested: JNK-IN-8 (1410880-22-6)
* Your question
* Name
* Email
Verification Code