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JW74

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For Research Use Only | Not For Clinical Use
CATAP863405601
CAS863405-60-1
MDL NumberMFCD07048962
Molecular Weight456.52
InChI KeyKRIKILRRJCIWNB-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Characterization of Hit Compounds Identified From High-throughput Screening for Their Effect on Blood-brain Barrier Integrity and Amyloid-β Clearance: In Vitro and In Vivo Studies

Khaled H Elfakhri, Quoc-Viet Duong, Courtney Langley, Ashley Depaula, Youssef M Mousa, Trista Lebeouf, Courtney Cain, Amal Kaddoumi

Neuroscience. 2018 May 21;379:269-280.

PMID: 29596966

1

The Iron Pro-Chelator BHAPI Attenuates Glutamate-Induced Oxidative Stress via Wnt-β/catenin Pathway in HT22 Cells

Fei Gao, Bao Wang, Tao Chang, Min Li, Wei Fang, Zhi-Hong Li, Li Gao

Brain Res Bull. 2018 May;139:285-291.

PMID: 29588166

1

The Long Non-Coding RNA LINC01606 Contributes to the Metastasis and Invasion of Human Gastric Cancer and Is Associated With Wnt/β-catenin Signaling

Yajun Luo, Wang Tan, Weikun Jia, Zilin Liu, Pengcheng Ye, Zhiming Fu, Fei Lu, Wanping Xiang, Linghan Tang, Lin Yao, Qingmei Huang, Jiangwei Xiao

Int J Biochem Cell Biol. 2018 Oct;103:125-134.

PMID: 30142387

1

The Tankyrase-Specific Inhibitor JW74 Affects Cell Cycle Progression and Induces Apoptosis and Differentiation in Osteosarcoma Cell Lines

Eva Wessel Stratford, Jeanette Daffinrud, Else Munthe, Russell Castro, Jo Waaler, Stefan Krauss, Ola Myklebost

Cancer Med. 2014 Feb;3(1):36-46.

PMID: 24403055

1

Wnt/β-catenin Signaling Pathway Activation Is Required for Proliferation of Chicken Primordial Germ Cells in Vitro

Hyung Chul Lee, Sumi Lim, Jae Yong Han

Sci Rep. 2016 Sep 30;6:34510.

PMID: 27687983

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