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K6PC-5

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For Research Use Only | Not For Clinical Use
CATAP756875511
CAS756875-51-1
Molecular Weight343.50
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Activation of SphK1 by K6PC-5 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Myocardial Cell Death

Jun-jie Shao, Yi Peng, Li-ming Wang, Jian-kai Wang, Xin Chen

DNA Cell Biol. 2015 Nov;34(11):669-76.

PMID: 26308910

1

K6PC-5 Activates SphK1-Nrf2 Signaling to Protect Neuronal Cells From Oxygen Glucose Deprivation/Re-Oxygenation

Hua Liu, Zhiqing Zhang, Min Xu, Rong Xu, Zhichun Wang, Guangfu Di

Cell Physiol Biochem. 2018;51(4):1908-1920.

PMID: 30504702

1

K6PC-5, a Direct Activator of Sphingosine Kinase 1, Promotes Epidermal Differentiation Through Intracellular Ca2+ Signaling

Jeong Hee Hong, Jong-Kyung Youm, Mi Jung Kwon, Byeong Deog Park, Yong-Moon Lee, Syng-Ill Lee, Dong Min Shin, Seung Hun Lee

J Invest Dermatol. 2008 Sep;128(9):2166-78.

PMID: 18385762

1

K6PC-5, a Novel Sphingosine Kinase 1 (SphK1) Activator, Alleviates Dexamethasone-Induced Damages to Osteoblasts Through Activating SphK1-Akt Signaling

Feng Ji, Li Mao, Yuanyuan Liu, Xiaojian Cao, Yue Xie, Shouguo Wang, Haodong Fei

Biochem Biophys Res Commun. 2015 Mar 13;458(3):568-575.

PMID: 25680461

1

Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model

Alba Di Pardo, Giuseppe Pepe, Salvatore Castaldo, Federico Marracino, Luca Capocci, Enrico Amico, Michele Madonna, Susy Giova, Se Kyoo Jeong, Bu-Mahn Park, Byeong Deog Park, Vittorio Maglione

Front Mol Neurosci. 2019 Apr 24;12:100.

PMID: 31068790

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