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kb-NB142-70

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For Research Use Only | Not For Clinical Use
CATAP1233533044
CAS1233533-04-4
Structure
MDL NumberMFCD18086915
Molecular Weight251.32
InChI KeyDHUAGGSHTKPOHU-UHFFFAOYSA-N
Description≥97% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥97% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

In Vitro Cytotoxicity, Pharmacokinetics, Tissue Distribution, and Metabolism of Small-Molecule Protein Kinase D Inhibitors, kb-NB142-70 and kb-NB165-09, in Mice Bearing Human Cancer Xenografts

Jianxia Guo, Dana M Clausen, Jan H Beumer, Robert A Parise, Merrill J Egorin, Karla Bravo-Altamirano, Peter Wipf, Elizabeth R Sharlow, Qiming Jane Wang, Julie L Eiseman

Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44.

PMID: 23108699

1

Novel Protein Kinase D Inhibitors Cause Potent Arrest in Prostate Cancer Cell Growth and Motility

Courtney R Lavalle, Karla Bravo-Altamirano, Karthik V Giridhar, Jun Chen, Elizabeth Sharlow, John S Lazo, Peter Wipf, Q Jane Wang

BMC Chem Biol. 2010 May 5;10:5.

PMID: 20444281

1

Protein Kinase D as a Potential Chemotherapeutic Target for Colorectal Cancer

Ning Wei, Edward Chu, Peter Wipf, John C Schmitz

Mol Cancer Ther. 2014 May;13(5):1130-41.

PMID: 24634417

1

Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D

Karla Bravo-Altamirano, Kara M George, Marie-Céline Frantz, Courtney R Lavalle, Manuj Tandon, Stephanie Leimgruber, Elizabeth R Sharlow, John S Lazo, Q Jane Wang, Peter Wipf

ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.

PMID: 21617763

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