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Ki11502

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For Research Use Only | Not For Clinical Use
CATAP347155764-A
CAS347155-76-4
MDL NumberMFCD12032139
Molecular Weight473.54
InChI KeyZXGIBSBJQLLUEE-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Blockade of the PDGFR Family Together With SRC Leads to Diminished Proliferation of Colorectal Cancer Cells

Silke Kaulfuß, Henning Seemann, Rovena Kampe, Julia Meyer, Ralf Dressel, Britta König, Jens-Gerd Scharf, Peter Burfeind

Oncotarget. 2013 Jul;4(7):1037-49.

PMID: 23900414

1

Characterisation of Ki11502 as a Potent Inhibitor of PDGF Beta Receptor-Mediated Proteoglycan Synthesis in Vascular Smooth Muscle Cells

Robel Getachew, Mandy L Ballinger, Micah L Burch, Peter J Little, Narin Osman

Eur J Pharmacol. 2010 Jan 25;626(2-3):186-92.

PMID: 19818754

1

Genistein Inhibits PDGF-stimulated Proteoglycan Synthesis in Vascular Smooth Muscle Without Blocking PDGFβ Receptor Phosphorylation

Peter J Little, Robel Getachew, Hossein Babaahmadi Rezaei, Estella Sanchez-Guerrero, Levon M Khachigian, Haitao Wang, Sufen Liao, Wenhua Zheng, Mandy L Ballinger, Narin Osman

Arch Biochem Biophys. 2012 Sep 1;525(1):25-31.

PMID: 22683649

1

Ki11502, a Novel Multitargeted Receptor Tyrosine Kinase Inhibitor, Induces Growth Arrest and Apoptosis of Human Leukemia Cells in Vitro and in Vivo

Chie Nishioka, Takayuki Ikezoe, Jing Yang, Atsushi Miwa, Taizo Tasaka, Yoshio Kuwayama, Kazuto Togitani, H Phillip Koeffler, Akihito Yokoyama

Blood. 2008 May 15;111(10):5086-92.

PMID: 18309036

1

Platelet-derived Growth Factor-Stimulated Versican Synthesis but Not Glycosaminoglycan Elongation in Vascular Smooth Muscle Is Mediated via Akt Phosphorylation

Narin Osman, Robel Getachew, Lyna Thach, Haitao Wang, Xiaoying Su, Wenhua Zheng, Peter J Little

Cell Signal. 2014 May;26(5):912-6.

PMID: 24462709

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