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KKL-35

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For Research Use Only | Not For Clinical Use
CATAP865285296
CAS865285-29-6
Molecular Weight317.70
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Genetic Tool to Quantify trans-Translation Activity in Vivo

Kevin Macé, Fanny Demay, Charlotte Guyomar, Sylvie Georgeault, Emmanuel Giudice, Renan Goude, Annie Trautwetter, Gwennola Ermel, Carlos Blanco, Reynald Gillet

J Mol Biol. 2017 Nov 24;429(23):3617-3625.

PMID: 29031699

1

KKL-35 Exhibits Potent Antibiotic Activity against Legionella Species Independently of trans-Translation Inhibition

Romain Brunel, Ghislaine Descours, Isabelle Durieux, Patricia Doublet, Sophie Jarraud, Xavier Charpentier

Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01459-17.

PMID: 29158279

1

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium Tuberculosis Cells

John N Alumasa, Paolo S Manzanillo, Nicholas D Peterson, Tricia Lundrigan, Anthony D Baughn, Jeffery S Cox, Kenneth C Keiler

ACS Infect Dis. 2017 Sep 8;3(9):634-644.

PMID: 28762275

1

Small Molecule Inhibitors of Trans-Translation Have Broad-Spectrum Antibiotic Activity

Nitya S Ramadoss, John N Alumasa, Lin Cheng, Yu Wang, Sharon Li, Benjamin S Chambers, Hoon Chang, Arnab K Chatterjee, Achim Brinker, Ingo H Engels, Kenneth C Keiler

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10282-7.

PMID: 23733947

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