KNK437

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For Research Use Only | Not For Clinical Use

CAT	AP218924255
CAS	218924-25-5
Structure
Molecular Weight	245.23

Description	≥98% (HPLC)
Solubility	DMSO: 5 mg/mL, clear (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	room temp

KNK437 Downregulates Heat Shock Protein 27 of Pancreatic Cancer Cells and Enhances the Cytotoxic Effect of Gemcitabine

Kumiko Taba, Yasuhiro Kuramitsu, Shomei Ryozawa, Kanako Yoshida, Toshiyuki Tanaka, Sayaka Mori-Iwamoto, Shin-ichiro Maehara, Yoshihiko Maehara, Isao Sakaida, Kazuyuki Nakamura

Chemotherapy. 2011;57(1):12-6.

PMID: 21124027

KNK437 Inhibits Replication and Transcription of the Hepatitis B Virus

Kanghong Hu, Yayun Huang, Jingfang Mu, Zhikui Cheng, Xiang Zhu

Bing Du Xue Bao. 2017 Jan;33(1):24-35.

PMID: 30702818

KNK437, a Benzylidene Lactam Compound, Sensitises Prostate Cancer Cells to the Apoptotic Effect of Hyperthermia

Emel Sahin, Mehmet Sahin, Ahter Dilsad Sanlioğlu, Saadet Gümüslü

Int J Hyperthermia. 2011;27(1):63-73.

PMID: 21204621

KNK437, Abrogates Hypoxia-Induced Radioresistance by Dual Targeting of the AKT and HIF-1α Survival Pathways

Deepu Oommen, Kevin M Prise

Biochem Biophys Res Commun. 2012 May 11;421(3):538-43.

PMID: 22521642

The Heat Shock Protein Inhibitor KNK437 Induces Neurite Outgrowth in PC12 Cells

Tomoko Koike, Shigeyuki Uno, Michiyasu Ishizawa, Hideo Takahashi, Kazumasa Ikeda, Shinichi Yokota, Makoto Makishima

Neurosci Lett. 2006 Dec 27;410(3):212-7.

PMID: 17055158

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