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KNK437

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For Research Use Only | Not For Clinical Use
CATAP218924255
CAS218924-25-5
Structure
Molecular Weight245.23
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

KNK437 Downregulates Heat Shock Protein 27 of Pancreatic Cancer Cells and Enhances the Cytotoxic Effect of Gemcitabine

Kumiko Taba, Yasuhiro Kuramitsu, Shomei Ryozawa, Kanako Yoshida, Toshiyuki Tanaka, Sayaka Mori-Iwamoto, Shin-ichiro Maehara, Yoshihiko Maehara, Isao Sakaida, Kazuyuki Nakamura

Chemotherapy. 2011;57(1):12-6.

PMID: 21124027

1

KNK437 Inhibits Replication and Transcription of the Hepatitis B Virus

Kanghong Hu, Yayun Huang, Jingfang Mu, Zhikui Cheng, Xiang Zhu

Bing Du Xue Bao. 2017 Jan;33(1):24-35.

PMID: 30702818

1

KNK437, a Benzylidene Lactam Compound, Sensitises Prostate Cancer Cells to the Apoptotic Effect of Hyperthermia

Emel Sahin, Mehmet Sahin, Ahter Dilsad Sanlioğlu, Saadet Gümüslü

Int J Hyperthermia. 2011;27(1):63-73.

PMID: 21204621

1

KNK437, Abrogates Hypoxia-Induced Radioresistance by Dual Targeting of the AKT and HIF-1α Survival Pathways

Deepu Oommen, Kevin M Prise

Biochem Biophys Res Commun. 2012 May 11;421(3):538-43.

PMID: 22521642

1

The Heat Shock Protein Inhibitor KNK437 Induces Neurite Outgrowth in PC12 Cells

Tomoko Koike, Shigeyuki Uno, Michiyasu Ishizawa, Hideo Takahashi, Kazumasa Ikeda, Shinichi Yokota, Makoto Makishima

Neurosci Lett. 2006 Dec 27;410(3):212-7.

PMID: 17055158

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