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KT 5823

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For Research Use Only | Not For Clinical Use
CATAP126643376-A
CAS126643-37-6
MDL NumberMFCD09878278
Molecular Weight495.53
InChI KeyQTYMDECKVKSGSM-YMUMJAELSA-N
Description≥85% (HPLC), lyophilized powder
Solubilityethyl acetate: 5 mg/mL
Assay≥85% (HPLC)
Colorwhite
Formlyophilized powder
Size100UG
Storage Conditions2-8°C
1

Dipeptidyl peptidase-4 Inhibitor Sitagliptin Induces Vasorelaxation via the Activation of Kv Channels and PKA

Hongliang Li, Mi Seon Seo, Jin Ryeol An, Hee Seok Jung, Kwon-Soo Ha, Eun-Taek Han, Seok-Ho Hong, Young Min Bae, Sung Hun Na, Won Sun Park

Toxicol Appl Pharmacol. 2019 Dec 1;384:114799.

PMID: 31678606

1

Involvement of Brain Natriuretic Peptide Signaling Pathway in the Cardioprotective Action of Sitagliptin

Samah S Abbas, Hesham M Mahmoud, Mona F Schaalan, Hanan S El-Abhar

Pharmacol Rep. 2018 Aug;70(4):720-729.

PMID: 29935398

1

Protein Kinases G Are Essential Downstream Mediators of the Antifibrotic Effects of sGC Stimulators

Alexandru-Emil Matei, Christian Beyer, Andrea-Hermina Györfi, Alina Soare, Chih-Wei Chen, Clara Dees, Christina Bergmann, Andreas Ramming, Andreas Friebe, Franz Hofmann, Oliver Distler, Georg Schett, Jörg H W Distler

Ann Rheum Dis. 2018 Mar;77(3):459.

PMID: 29311148

1

The Anti-Diabetic Drug Dapagliflozin Induces Vasodilation via Activation of PKG and Kv Channels

Hongliang Li, Sung Eun Shin, Mi Seon Seo, Jin Ryeol An, Il-Whan Choi, Won-Kyo Jung, Amy L Firth, Dae-Sung Lee, Mi-Jin Yim, Grace Choi, Jeong Min Lee, Sung Hun Na, Won Sun Park

Life Sci. 2018 Mar 15;197:46-55.

PMID: 29409796

1

The bradykinin-cGMP-PKG Pathway Augments Insulin Sensitivity via Upregulation of MAPK phosphatase-5 and Inhibition of JNK

María E Frigolet, Garry Thomas, Kristin Beard, Huogen Lu, Lijiang Liu, I George Fantus

Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E321-E334.

PMID: 28679626

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