CAS 938440-64-3 KU 0063794 - Analytical Products / Alfa Chemistry

CAT	AP938440643-A
CAS	938440-64-3
MDL Number	MFCD11977741
Molecular Weight	465.54
InChI Key	RFSMUFRPPYDYRD-CALCHBBNSA-N

Description	≥98% (HPLC)
Solubility	DMSO: >2 mg/mL (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

1

Autophagy Inhibition Sensitizes KU-0063794-mediated anti-HepG2 Hepatocellular Carcinoma Cell Activity in Vitro and in Vivo

Tong Yongxi, Huang Haijun, Zheng Jiaping, Shao Guoliang, Pan Hongying

Biochem Biophys Res Commun. 2015 Sep 25;465(3):494-500.

PMID: 26278819

1

Identification and Application of Gene Expression Signatures Associated With Lifespan Extension

Alexander Tyshkovskiy, Perinur Bozaykut, Anastasia A Borodinova, Maxim V Gerashchenko, Gene P Ables, Michael Garratt, Philipp Khaitovich, Clary B Clish, Richard A Miller, Vadim N Gladyshev

Cell Metab. 2019 Sep 3;30(3):573-593.e8.

PMID: 31353263

1

Ku-0063794 Is a Specific Inhibitor of the Mammalian Target of Rapamycin (mTOR)

Juan M García-Martínez, Jennifer Moran, Rosemary G Clarke, Alex Gray, Sabina C Cosulich, Christine M Chresta, Dario R Alessi

Biochem J. 2009 Jun 12;421(1):29-42.

PMID: 19402821

1

mTORC1 Inhibition Attenuates Necroptosis Through RIP1 Inhibition-Mediated TFEB Activation

Koki Abe, Toshiyuki Yano, Masaya Tanno, Takayuki Miki, Atsushi Kuno, Tatsuya Sato, Hidemichi Kouzu, Kei Nakata, Wataru Ohwada, Yukishige Kimura, Hirohito Sugawara, Satoru Shibata, Yusuke Igaki, Shoya Ino, etc.

Biochim Biophys Acta Mol Basis Dis. 2019 Dec 1;1865(12):165552.

PMID: 31499159

1

Potent Dual Inhibitors of TORC1 and TORC2 Complexes (KU-0063794 and KU-0068650) Demonstrate in Vitro and Ex Vivo Anti-Keloid Scar Activity

Farhatullah Syed, Hitesh J Sanganee, Subir Singh, Ashwani Bahl, Ardeshir Bayat

J Invest Dermatol. 2013 May;133(5):1340-50.

PMID: 23303455

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