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KU-55933

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For Research Use Only | Not For Clinical Use
CATAP587871269
CAS587871-26-9
MDL NumberMFCD08276985
Molecular Weight395.49
InChI KeyXRKYMMUGXMWDAO-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

ATM Inhibitor KU-55933 Increases the TMZ Responsiveness of Only Inherently TMZ Sensitive GBM Cells

Aditi Nadkarni, Meena Shrivastav, Ann C Mladek, Paul M Schwingler, Patrick T Grogan, Junjie Chen, Jann N Sarkaria

J Neurooncol. 2012 Dec;110(3):349-57.

PMID: 23054561

1

Evaluation of ATM Kinase Inhibitor KU-55933 as Potential Anti- Toxoplasma gondii Agent

Jonathan Munera López, Agustina Ganuza, Silvina S Bogado, Daniela Muñoz, Diego M Ruiz, William J Sullivan Jr, Laura Vanagas, Sergio O Angel

Front Cell Infect Microbiol. 2019 Feb 13;9:26.

PMID: 30815397

1

Synergistic Antitumor Effect of Sorafenib in Combination With ATM Inhibitor in Hepatocellular Carcinoma Cells

Jianhua Liu, Yahui Liu, Lingyu Meng, Bai Ji, Daqing Yang

Int J Med Sci. 2017 Apr 9;14(6):523-529.

PMID: 28638267

1

The ATM Kinase Inhibitor KU-55933 Provides Neuroprotection Against Hydrogen Peroxide-Induced Cell Damage via a γH2AX/p-p53/caspase-3-independent Mechanism: Inhibition of Calpain and Cathepsin D

Jakub Chwastek, Danuta Jantas, Władysław Lasoń

Int J Biochem Cell Biol. 2017 Jun;87:38-53.

PMID: 28341201

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