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L-701,324

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For Research Use Only | Not For Clinical Use
CATAP142326598
CAS142326-59-8
Structure
MDL NumberMFCD00910917
Molecular Weight363.79
InChI KeyFLVRDMUHUXVRET-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: 36.4 mg/mL
Assay≥98% (HPLC)
Formsolid
Size10MG, 50MG
1

Anticonvulsant and Behavioral Profile of L-701,324, a Potent, Orally Active Antagonist at the Glycine Modulatory Site on the N-methyl-D-aspartate Receptor Complex

L J Bristow, P H Hutson, J J Kulagowski, P D Leeson, S Matheson, F Murray, D Rathbone, K L Saywell, L Thorn, A P Watt, M D Tricklebank

J Pharmacol Exp Ther. 1996 Nov;279(2):492-501.

PMID: 8930150

1

Effects of L-701,324, a High-Affinity Antagonist at the N-methyl-D-aspartate (NMDA) Receptor Glycine Site, on the Rat Electroencephalogram

T P Obrenovitch, A M Hardy, E Zilkha

Naunyn Schmiedebergs Arch Pharmacol. 1997 Jun;355(6):779-86.

PMID: 9205964

1

Electrophysiological Characterisation of the Antagonist Properties of Two Novel NMDA Receptor Glycine Site Antagonists, L-695,902 and L-701,324

T Priestley, P Laughton, A J Macaulay, R G Hill, J A Kemp

Neuropharmacology. 1996;35(11):1573-81.

PMID: 9025105

1

Inhibition of Cortical Spreading Depression by L-701,324, a Novel Antagonist at the Glycine Site of the N-methyl-D-aspartate Receptor Complex

T P Obrenovitch, E Zilkha

Br J Pharmacol. 1996 Mar;117(5):931-7.

PMID: 8851513

1

L-701,324, a Selective Antagonist at the Glycine Site of the NMDA Receptor, Counteracts Haloperidol-Induced Muscle Rigidity in Rats

J Konieczny, K Ossowska, G Schulze, H Coper, S Wolfarth

Psychopharmacology (Berl). 1999 Apr;143(3):235-43.

PMID: 10353425

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