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L-741,626

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For Research Use Only | Not For Clinical Use
CATAP81226600
CAS81226-60-0
MDL NumberMFCD00953632
Molecular Weight340.85
InChI KeyLLBLNMUONVVVPG-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL; ethanol: 24 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size10MG, 50MG
Storage Conditionsroom temp
1

Antagonism of the Effects of (+)-PD 128907 on Midbrain Dopamine Neurones in Rat Brain Slices by a Selective D2 Receptor Antagonist L-741,626

B J Bowery, Z Razzaque, F Emms, S Patel, S Freedman, L Bristow, J Kulagowski, G R Seabrook

Br J Pharmacol. 1996 Dec;119(7):1491-7.

PMID: 8968560

1

Functional Lateralization in the Prefrontal Cortex of Dopaminergic Modulation of Memory Consolidation

Mariusz Papp, Piotr Gruca, Magdalena Lason, Monika Niemczyk, Paul Willner

Behav Pharmacol. 2019 Sep;30(6):514-520.

PMID: 31033526

1

Human D2 and D4 Dopamine Receptors Couple Through Betagamma G-protein Subunits to Inwardly Rectifying K+ Channels (GIRK1) in a Xenopus Oocyte Expression System: Selective Antagonism by L-741,626 and L-745,870 Respectively

G Pillai, N A Brown, G McAllister, G Milligan, G R Seabrook

Neuropharmacology. 1998 Aug;37(8):983-7.

PMID: 9833627

1

Newly Developed Dopamine D 3 Receptor Antagonists, R-VK4-40 and R-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats

Chloe J Jordan, Bree A Humburg, Eric B Thorndike, Anver Basha Shaik, Zheng-Xiong Xi, Michael H Baumann, Amy Hauck Newman, Charles W Schindler

J Pharmacol Exp Ther. 2019 Dec;371(3):602-614.

PMID: 31562201

1

Synthesis and Characterization of Selective Dopamine D2 Receptor Antagonists. 2. Azaindole, Benzofuran, and Benzothiophene Analogs of L-741,626

Suwanna Vangveravong, Michelle Taylor, Jinbin Xu, Jinquan Cui, Wesley Calvin, Sonja Babic, Robert R Luedtke, Robert H Mach

Bioorg Med Chem. 2010 Jul 15;18(14):5291-300.

PMID: 20542439

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