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L-Thyroxine (T4) solution

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For Research Use Only | Not For Clinical Use
CATAP51489-A
CAS51-48-9
Structure
MDL NumberMFCD00002595
Molecular Weight776.87
InChI KeyXUIIKFGFIJCVMT-LBPRGKRZSA-N
REAXYS Number2228515
Description100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material
Gradecertified reference material
Linear FormulaHOC6H2(I)2OC6H2(I)2CH2CH(NH2)CO2H
MP223 °C (dec.) (lit.)
Size1ML
Storage Conditions−20°C
1

[Bioequivalence of L-thyroxine Tablets and a Liquid L-thyroxine Solution in the Treatment of Hypothyroid Patients]

Martin Grussendorf, Renate Vaupel, Karl Wegscheider

Med Klin (Munich). 2004 Nov 15;99(11):639-44.

PMID: 15583873

1

Liquid and Softgel Capsules of L-Thyroxine Results Lower Serum Thyrotropin Levels More Than Tablet Formulations in Hypothyroid Patients

Salvatore Benvenga

J Clin Transl Endocrinol. 2019 Aug 6;18:100204.

PMID: 31844631

1

Pharmacokinetics of Total Thyroxine After Repeated Oral Administration of Levothyroxine Solution and Its Clinical Efficacy in Hypothyroid Dogs

I C van Dijl, G Le Traon, B D A M van de Meulengraaf, S Burgaud, L J I Horspool, H S Kooistra

J Vet Intern Med. Jul-Aug 2014;28(4):1229-34.

PMID: 24773132

1

Pharmacokinetics of Total Thyroxine in Dogs After Administration of an Oral Solution of Levothyroxine Sodium

G Le Traon, S Burgaud, L J I Horspool

J Vet Pharmacol Ther. 2008 Apr;31(2):95-101.

PMID: 18307500

1

The Administration of L-thyroxine as Soft Gel Capsule or Liquid Solution

Roberto Vita, Poupak Fallahi, Alessandro Antonelli, Salvatore Benvenga

Expert Opin Drug Deliv. 2014 Jul;11(7):1103-11.

PMID: 24896369

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