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Lapatinib

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For Research Use Only | Not For Clinical Use
CATAP231277922
CAS231277-92-2
Structure
MDL NumberMFCD09264194
Molecular Weight581.06
InChI KeyBCFGMOOMADDAQU-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Efficacy and Safety of Lapatinib and Trastuzumab for HER2-positive Breast Cancer: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

Zhi-Qiao Xu, Yan Zhang, Ning Li, Pei-Jie Liu, Ling Gao, Xin Gao, Xiao-Jing Tie

BMJ Open. 2017 Mar 13;7(3):e013053.

PMID: 28289045

1

Lapatinib

Minna Voigtlaender, Tanja Schneider-Merck, Martin Trepel

Recent Results Cancer Res. 2018;211:19-44.

PMID: 30069757

1

Lapatinib With Trastuzumab for HER2-positive Early Breast Cancer (NeoALTTO): A Randomised, Open-Label, Multicentre, Phase 3 Trial

José Baselga, Ian Bradbury, Holger Eidtmann, Serena Di Cosimo, Evandro de Azambuja, Claudia Aura, Henry Gómez, Phuong Dinh, Karine Fauria, Veerle Van Dooren, Gursel Aktan, Aron Goldhirsch, Tsai-Wang Chang, etc.

Lancet. 2012 Feb 18;379(9816):633-40.

PMID: 22257673

1

Mechanisms of Lapatinib Resistance in HER2-driven Breast Cancer

Valentina D'Amato, Lucia Raimondo, Luigi Formisano, Mario Giuliano, Sabino De Placido, Roberta Rosa, Roberto Bianco

Cancer Treat Rev. 2015 Dec;41(10):877-83.

PMID: 26276735

1

Overall Survival Benefit With Lapatinib in Combination With Trastuzumab for Patients With Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer: Final Results From the EGF104900 Study

Kimberly L Blackwell, Harold J Burstein, Anna Maria Storniolo, Hope S Rugo, George Sledge, Gursel Aktan, Catherine Ellis, Allison Florance, Svetislava Vukelja, Joachim Bischoff, José Baselga, Joyce O'Shaughnessy

J Clin Oncol. 2012 Jul 20;30(21):2585-92.

PMID: 22689807

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