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Linopirdine

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For Research Use Only | Not For Clinical Use
CATAP105431729
CAS105431-72-9
Structure
MDL NumberMFCD00867216
Molecular Weight391.46
InChI KeyYEJCDKJIEMIWRQ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >10 mg/mL; ethanol: 240 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Size10MG, 50MG
1

[3H]linopirdine Binding to Rat Brain Membranes Is Not Relevant for M-channel Interaction

Christian Wolff, Michel Gillard, Bruno Fuks, Pierre Chatelain

Eur J Pharmacol. 2005 Jul 25;518(1):10-7.

PMID: 16018996

1

Effects of the Kv7 Voltage-Activated Potassium Channel Inhibitor Linopirdine in Rat Models of Haemorrhagic Shock

Sean P Nassoiy, Favin S Babu, Heather M LaPorte, Kenneth L Byron, Matthias Majetschak

Clin Exp Pharmacol Physiol. 2018 Apr 27;10.1111/1440-1681.12958.

PMID: 29702725

1

Neural KCNQ (Kv7) Channels

David A Brown, Gayle M Passmore

Br J Pharmacol. 2009 Apr;156(8):1185-95.

PMID: 19298256

1

The M-channel Blocker Linopirdine Is an Agonist of the Capsaicin Receptor TRPV1

Cristian Neacsu, Alexandru Babes

J Pharmacol Sci. 2010;114(3):332-40.

PMID: 21099148

1

XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels That Favor Activated Single Subunits

Derek L Greene, Seungwoo Kang, Naoto Hoshi

J Pharmacol Exp Ther. 2017 Jul;362(1):177-185.

PMID: 28483800

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