LKB1/MO25/STRAD Active human

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For Research Use Only | Not For Clinical Use

CAT

IAR42416144

Description	recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE)
Assay	≥70% (SDS-PAGE)
Form	aqueous solution; 66 kDa (MO25); 74 kDa (STRAD); NM_001003787 (STRAD); NM_016289 (MO25)
Size	20μG
Storage Conditions	−70°C

ATP and MO25alpha Regulate the Conformational State of the STRADalpha Pseudokinase and Activation of the LKB1 Tumour Suppressor

Elton Zeqiraj, Beatrice Maria Filippi, Simon Goldie, Iva Navratilova, Jérôme Boudeau, Maria Deak, Dario R Alessi, Daan M F van Aalten

PLoS Biol. 2009 Jun 9;7(6):e1000126.

PMID: 19513107

Complexes Between the LKB1 Tumor Suppressor, STRAD alpha/beta and MO25 alpha/beta Are Upstream Kinases in the AMP-activated Protein Kinase Cascade

Simon A Hawley, Jérôme Boudeau, Jennifer L Reid, Kirsty J Mustard, Lina Udd, Tomi P Mäkelä, Dario R Alessi, D Grahame Hardie

J Biol. 2003;2(4):28.

PMID: 14511394

LKB1 Is a Master Kinase That Activates 13 Kinases of the AMPK Subfamily, Including MARK/PAR-1

Jose M Lizcano, Olga Göransson, Rachel Toth, Maria Deak, Nick A Morrice, Jérôme Boudeau, Simon A Hawley, Lina Udd, Tomi P Mäkelä, D Grahame Hardie, Dario R Alessi

EMBO J. 2004 Feb 25;23(4):833-43.

PMID: 14976552

The Ubiquitin-Associated Domain of AMPK-related Kinases Regulates Conformation and LKB1-mediated Phosphorylation and Activation

Mahaboobi Jaleel, Fabrizio Villa, Maria Deak, Rachel Toth, Alan R Prescott, Daan M F Van Aalten, Dario R Alessi

Biochem J. 2006 Mar 15;394(Pt 3):545-55.

PMID: 16396636

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