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LMT-28

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For Research Use Only | Not For Clinical Use
CATAP1239600180
CAS1239600-18-0
Molecular Weight311.42
InChI KeyUDXWSYOXIRPYFK-RRFJBIMHSA-N
Description≥98% (HPLC)
Assay≥98% (HPLC)
Colorcolorless to light yellow, oil
Formoil
Size5MG, 25MG
Storage Conditions−20°C
1

A Directly GP130-targeting Small Molecule Ameliorates Collagen-Induced Arthritis (CIA) by Inhibiting IL-6/GP130 Signalling and Th17 Differentiation

Yeon-Hwa Park, Hee Jung Kim, Tae-Hwe Heo

Clin Exp Pharmacol Physiol. 2020 Apr;47(4):628-639.

PMID: 31742738

1

A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130

Soon-Sun Hong, Jung Ho Choi, Sung Yoon Lee, Yeon-Hwa Park, Kyung-Yeon Park, Joo Young Lee, Juyoung Kim, Veeraswamy Gajulapati, Ja-Il Goo, Sarbjit Singh, Kyeong Lee, Young-Kook Kim, So Hee Im, Sung-Hoon Ahn, etc.

J Immunol. 2015 Jul 1;195(1):237-45.

PMID: 26026064

1

Combination of gp130-targeting and TNF-targeting Small Molecules in Alleviating Arthritis Through the Down-Regulation of Th17 Differentiation and Osteoclastogenesis

Yeon-Hwa Park, Hee Jung Kim, Kyeong Lee, Yongseok Choi, Tae-Hwe Heo

Biochem Biophys Res Commun. 2020 Feb 19;522(4):1030-1036.

PMID: 31818460

1

Cytochrome C Oxidase Dysfunction Enhances Phagocytic Function and Osteoclast Formation in Macrophages

Rajesh Angireddy, Hasan Raza Kazmi, Satish Srinivasan, Li Sun, Jameel Iqbal, Serge Y Fuchs, Manti Guha, Takashi Kijima, Tony Yuen, Mone Zaidi, Narayan G Avadhani

FASEB J. 2019 Aug;33(8):9167-9181.

PMID: 31063702

1

In Vitro and in Vivo Pharmacokinetic Characterization of LMT-28 as a Novel Small Molecular interleukin-6 Inhibitor

Sung-Hoon Ahn, Tae-Hwe Heo, Hyun-Sik Jun, Yongseok Choi

Asian-Australas J Anim Sci. 2020 Apr;33(4):670-677.

PMID: 31480155

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