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Longdaysin

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For Research Use Only | Not For Clinical Use
CATIAR42415291
Molecular Weight335.33
DescriptionA cell-permeable purine compound that acts as a reversible and ATP-competitive dual inhibitor of CKIα and CKIδ activities with moderate selectivity over Cdk7 and Erk2.
SolubilityDMSO: 50 mg/mL
Assay≥99% (HPLC)
Colorwhite
Formsolid; protect from light
Size10MG
Storage Conditions+2C to +8C
1

A Synchronized Circadian Clock Enhances Early Chondrogenesis

M Abdulhadi Alagha, Judit Vágó, Éva Katona, Roland Takács, Daan van der Veen, Róza Zákány, Csaba Matta

Cartilage. 2020 Feb 14;1947603520903425.

PMID: 32059614

1

Chemical Control of Mammalian Circadian Behavior Through Dual Inhibition of Casein Kinase Iα and δ

Jae Wook Lee, Tsuyoshi Hirota, Daisuke Ono, Sato Honma, Ken-Ichi Honma, Keunwan Park, Steve A Kay

J Med Chem. 2019 Feb 28;62(4):1989-1998.

PMID: 30707835

1

Controlling the Circadian Clock With High Temporal Resolution Through Photodosing

Dušan Kolarski, Akiko Sugiyama, Ghislain Breton, Christin Rakers, Daisuke Ono, Albert Schulte, Florence Tama, Kenichiro Itami, Wiktor Szymanski, Tsuyoshi Hirota, Ben L Feringa

J Am Chem Soc. 2019 Oct 9;141(40):15784-15791.

PMID: 31509406

1

High-throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

Tsuyoshi Hirota, Jae Wook Lee, Warren G Lewis, Eric E Zhang, Ghislain Breton, Xianzhong Liu, Michael Garcia, Eric C Peters, Jean-Pierre Etchegaray, David Traver, Peter G Schultz, Steve A Kay

PLoS Biol. 2010 Dec 14;8(12):e1000559.

PMID: 21179498

1

Longdaysin Inhibits Wnt/β-catenin Signaling and Exhibits Antitumor Activity Against Breast Cancer

Yanpeng Xiong, Liang Zhou, Zijie Su, Jiaxing Song, Qi Sun, Shan-Shan Liu, Yuqing Xia, Zhongyuan Wang, Desheng Lu

Onco Targets Ther. 2019 Feb 5;12:993-1005.

PMID: 30787621

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