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Lonidamine

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For Research Use Only | Not For Clinical Use
CATAP50264692
CAS50264-69-2
Structure
MDL NumberMFCD00866285
Molecular Weight321.16
EC Number256-510-0
InChI KeyWDRYRZXSPDWGEB-UHFFFAOYSA-N
Descriptionmitochondrial hexokinase inhibitor
Size5MG, 25MG
1

Drug Repurposing of Metabolic Agents in Malignant Glioma

Corinna Seliger, Peter Hau

Int J Mol Sci. 2018 Sep 14;19(9):2768.

PMID: 30223473

1

Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium Bromide (MTT) Assay When Compared to Three Commonly Used Cell Enumeration Assays

Alet van Tonder, Annie M Joubert, A Duncan Cromarty

BMC Res Notes. 2015 Feb 20;8:47.

PMID: 25884200

1

Mechanism of Antineoplastic Activity of Lonidamine

Kavindra Nath, Lili Guo, Bethany Nancolas, David S Nelson, Alexander A Shestov, Seung-Cheol Lee, Jeffrey Roman, Rong Zhou, Dennis B Leeper, Andrew P Halestrap, Ian A Blair, Jerry D Glickson

Biochim Biophys Acta. 2016 Dec;1866(2):151-162.

PMID: 27497601

1

Targeting Glucose Metabolism to Suppress Cancer Progression: Prospective of Anti-Glycolytic Cancer Therapy

Ali F Abdel-Wahab, Waheed Mahmoud, Randa M Al-Harizy

Pharmacol Res. 2019 Dec;150:104511.

PMID: 31678210

1

Targeting Lonidamine to Mitochondria Mitigates Lung Tumorigenesis and Brain Metastasis

Gang Cheng, Qi Zhang, Jing Pan, Yongik Lee, Olivier Ouari, Micael Hardy, Monika Zielonka, Charles R Myers, Jacek Zielonka, Katherine Weh, Andrew C Chang, Guoan Chen, Laura Kresty, Balaraman Kalyanaraman, etc.

Nat Commun. 2019 May 17;10(1):2205.

PMID: 31101821

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