LSD1 Active human - Analytical Products / Alfa Chemistry

CAT

IAR42416057

Description	recombinant, expressed in E. coli, ≥70% (SDS-PAGE)
Assay	≥70% (SDS-PAGE)
Form	aqueous solution
Size	50μG
Storage Conditions	−70°C

1

Design, Synthesis and in Vitro Evaluation of Stilbene Derivatives as Novel LSD1 Inhibitors for AML Therapy

Yingchao Duan, Wenping Qin, Fengzhi Suo, Xiaoyu Zhai, Yuanyuan Guan, Xiaojuan Wang, Yichao Zheng, Hongmin Liu

Bioorg Med Chem. 2018 Dec 15;26(23-24):6000-6014.

PMID: 30448189

1

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

Yujiang Shi, Fei Lan, Caitlin Matson, Peter Mulligan, Johnathan R Whetstine, Philip A Cole, Robert A Casero, Yang Shi

Cell. 2004 Dec 29;119(7):941-53.

PMID: 15620353

1

LPE-1, an Orally Active Pyrimidine Derivative, Inhibits Growth and Mobility of Human Esophageal Cancers by Targeting LSD1

Bo Wang, Bing Zhao, Lu-Ping Pang, Yuan-Di Zhao, Qian Guo, Jun-Wei Wang, Yi-Chao Zheng, Xin-Hui Zhang, Ying Liu, Guang-Yao Liu, Wen-Ge Guo, Chao Wang, Zhong-Hua Li, Xue-Jing Mao, Bin Yu, Li-Ying Ma, Hong-Min Liu

Pharmacol Res. 2017 Aug;122:66-77.

PMID: 28571892

1

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

Yong Yu, Kolja Schleich, Bin Yue, Sujuan Ji, Philipp Lohneis, Kristel Kemper, Mark R Silvis, Nouar Qutob, Ellen van Rooijen, Melanie Werner-Klein, Lianjie Li, Dhriti Dhawan, Svenja Meierjohann, Maurice Reimann, etc.

Cancer Cell. 2018 Feb 12;33(2):322-336.e8.

PMID: 29438700

1

The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells

William J Harris, Xu Huang, James T Lynch, Gary J Spencer, James R Hitchin, Yaoyong Li, Filippo Ciceri, Julian G Blaser, Brigit F Greystoke, Allan M Jordan, Crispin J Miller, Donald J Ogilvie, Tim C P Somervaille

Cancer Cell. 2012 Apr 17;21(4):473-87.

PMID: 22464800

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