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LSN2463359

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For Research Use Only | Not For Clinical Use
CATAP1401031524
CAS1401031-52-4
Molecular Weight265.31
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

In Vitro Characterisation of the Novel Positive Allosteric Modulators of the mGlu₅ Receptor, LSN2463359 and LSN2814617, and Their Effects on Sleep Architecture and Operant Responding in the Rat

Gary Gilmour, Lisa M Broad, Keith A Wafford, Thomas Britton, Ellen M Colvin, Adam Fivush, Francois Gastambide, Brian Getman, Beverly A Heinz, Andrew P McCarthy, Lourdes Prieto, Elaine Shanks, Janice W Smith, etc.

Neuropharmacology. 2013 Jan;64:224-39.

PMID: 22884720

1

MAM-E17 Rat Model Impairments on a Novel Continuous Performance Task: Effects of Potential Cognitive Enhancing Drugs

Adam C Mar, Simon R O Nilsson, Begoña Gamallo-Lana, Ming Lei, Theda Dourado, Johan Alsiö, Lisa M Saksida, Timothy J Bussey, Trevor W Robbins

Psychopharmacology (Berl). 2017 Oct;234(19):2837-2857.

PMID: 28744563

1

Selective Remediation of Reversal Learning Deficits in the Neurodevelopmental MAM Model of Schizophrenia by a Novel mGlu5 Positive Allosteric Modulator

Francois Gastambide, Marie-Caroline Cotel, Gary Gilmour, Michael J O'Neill, Trevor W Robbins, Mark D Tricklebank

Neuropsychopharmacology. 2012 Mar;37(4):1057-66.

PMID: 22129780

1

The mGlu₅ Positive Allosteric Modulator LSN2463359 Differentially Modulates Motor, Instrumental and Cognitive Effects of NMDA Receptor Antagonists in the Rat

Francois Gastambide, Gary Gilmour, Trevor W Robbins, Mark D Tricklebank

Neuropharmacology. 2013 Jan;64:240-7.

PMID: 22884612

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